What is thrombocytosis? Causes and symptoms

Our bodies are designed in such a way that each part of it carries a certain role. For example, the blood consists of a variety of structures, each of which performs its function. Platelets are one of the most important blood cells that are involved in stopping bleeding, eliminate damage to blood vessels and restore their integrity, gluing together and forming a clot at the site of damage, in addition, they are responsible for blood clotting. These small, nuclear-free cells play a huge role in our hematopoietic system, and without them any slightest bruise or bleeding could be fatal.

Table of Contents:
  • Causes of
  • Symptoms of thrombocytosis
  • Thrombocytosis in children
  • Treatment of thrombocytosis

The level of platelets in each person should be monitored by the results of the analysis. Low blood levels can threaten excessively liquid blood, and problems with stopping bleeding. But there is a reverse phenomenon, people have to find out what is thrombocytosis, when a large num

ber of platelets is found in their blood. This state does not promise anything good, because it means that the blood is too viscous and thick, which means that blood vessels can clog with blood clots. What are the causes and signs of thrombocytosis, the danger of this disease, and how to be, we will try to solve all these issues.

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Causes

Thrombocytosis is a condition of the blood when the platelet count exceeds 400 thousand per 11 mm3 of blood. There are 2 degrees of development of the disease:

  • primary thrombocytosis( or essential);
  • secondary thrombocytosis( or reactive).

The primary stage, or thrombocytosis, ICB 10( in the international classification of diseases) arises in connection with the disruption of stem cells in the bone marrow, which, in turn, causes a pathological proliferation of blood platelets in the blood. Essential thrombocytosis is extremely rare in children and adolescents, and is usually diagnosed in elderly people over 60 years of age. Such deviations are usually detected randomly, after the regular delivery of a general clinical blood test. The symptoms of primary thrombocytosis can be noted headaches, which often disturb the patient, but pathology may manifest differently in different people. This form of the disease can take a chronic course, with a slow but steady increase in the number of platelets. Without proper treatment, the patient may develop myelofibrosis when stem cells are transformed, or thromboembolism.

Reactive thrombocytosis or its secondary form develops against the background of any other pathological condition or disease. These can be injuries, inflammations, infections and other abnormalities. The most common causes of secondary thrombocytosis include:

  • Acute or chronic infectious diseases, including bacterial, fungal and viral( eg, meningitis, hepatitis, pneumonia, thrush, etc.);
  • Acute iron deficiency in the body( iron deficiency anemia);
  • Removal of the spleen;
  • The presence of a malignant tumor( especially of the lungs or pancreas);
  • Injuries, large blood loss, including after surgical interventions;
  • Various inflammations that trigger platelet splash into the blood( eg, sarcoidosis, spondyloarthritis, liver cirrhosis; collagenosis, etc.)

Occasionally, thrombocytosis occurs in pregnant women, in most cases it is considered a convertible condition and is explained by physiological reasons, such as an increase in total blood volume, a slowdown in metabolism or a decrease in the body's iron levels.

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Symptoms of thrombocytosis

Thrombocytosis for a long time may not manifest itself, and signs of the disease is easy to miss. However, due to a significant increase in the number of platelets, the microcirculatory processes, blood coagulability are disturbed in a person, problems with blood vessels and blood flow in the whole organism appear. The manifestation of thrombocytosis may vary in different patients. Most often, people with an increased number of platelets have the following complaints:

  • Weakness, lethargy, fatigue;
  • Visual impairment;
  • Frequent bleeding: from nose, uterine, intestinal( blood in feces);
  • Bluish skin tone;
  • Tissue swelling;
  • Cold hands and feet, tingling and pain in the tips of the fingers;
  • Uncaused hematomas and subcutaneous hemorrhages;
  • Visually thick and bulging veins;
  • Persistent itching.

Symptoms can occur both individually and in combination. Do not disregard each of the above symptoms, and contact a specialist for analysis and passing the survey, because the earlier the problem is identified, the easier it will be to fix it.

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Thrombocytosis in children

Despite the fact that thrombocytosis usually affects the adult population, in recent years there has been a tendency to an increase in the incidence of development of the disease in children. The causes of thrombocytosis in children are not much different from adults, it can occur due to a violation of stem cells, as a result of inflammatory, bacterial and infectious diseases, after injuries, blood loss or surgery. Thrombocytosis in an infant can develop on the background of dehydration, as well as in the presence of diseases characterized by increased bleeding. In addition, thrombocytosis in children under one year may be associated with a low content of hemoglobin in the blood, i.e.anemia.

If an increase in the permissible norms of platelet levels is detected, the treatment of this pathology begins with the adjustment of the baby's nutrition, if the situation does not change, special drug therapy is carried out.

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Treatment of thrombocytosis

Further recommendations of the doctor will depend on the severity and form of the disease.

In secondary thrombocytosis, the main task is to eliminate the root cause, which led to an increase in platelets, that is, get rid of the underlying disease.

If thrombocytosis is not associated with another disease, and is found to be an independent pathology, then further actions will depend on how critical the deviation from the norm is. With minor changes, it is recommended to change the diet. The diet should be saturated with products that reduce blood viscosity, such as:

  • all types of citrus;
  • sour berries;
  • tomatoes;
  • garlic and onion;
  • linseed and olive oil( instead of sunflower).

There is also a list of prohibited foods that thicken blood, these include: bananas, pomegranates, mangoes, rowan and wild rose berries, walnuts and lentils.

In addition to observing the diet, it is necessary to follow the drinking regime and use at least 2-2.5 liters per day, otherwise it will be difficult to achieve a positive result, since the blood thickens strongly when dehydrated.

If the power adjustment did not bring the proper result, and the rate is still high, then it is impossible to do without taking medication. Appointments should only be made by a specialist. Therapy, as a rule, includes taking medications that reduce blood clotting( anticoagulants and antiplatelet agents), as well as interferon and drugs with hydroxyurea.

If thrombocytosis occurs during pregnancy and its signs progress, then the woman is prescribed medications to improve uteroplacental blood flow.

Treatment of thrombocytosis with folk remedies, using decoctions of herbs and medicinal plants takes place, but only after consultation with your doctor. It is necessary to understand that some phyto-components can have a strong effect on the body and even aggravate the situation.

The most important thing that thrombocytosis is dangerous is the formation of clots and blood clots, which under fatal circumstances can be fatal. Therefore, at the first warning signs or detection of elevated levels of platelets in the blood, immediately proceed to treatment, modern methods and tools will help you quickly return the indicator to normal.

Take care of health!