What do they say elevated monocytes in the blood
Monocytes are large active cells belonging to leukocytes, whose main function is to protect the body against infections, microbes, fungi, and foreign bodies. But the fact that these cells help the body to defeat the disease, does not mean that the more of them, the better. An increase in monocytes is likely to indicate the presence of a disease.
- What are monocytes?
- Reasons for the increase of monocytes in the blood
What are monocytes?
Monocytes originate in the bone marrow, then they enter the blood for 2-3 days to purify it. During this period, young monocytes are particularly active and productive.
After this, the monocytes enter the tissues: spleen, liver, lymph nodes, where they continue their protective functions.
The mechanism of monocyte work is as follows: monocytes receive a signal from special cells that a pathogenic cell is found at a given place, the monocyte is sent there, captures the cell with its surface and destroys it i
Monocytes among other things:
- restore blood balance;
- normalize blood formation;
- promote tissue regeneration;
- retain immunity;
- provide protection against tumors;
- destroy old, spent monocytes from the surface of inflammation, replacing them with fresh cells.
Any condition in which the number of monocytes increases in comparison with the norm is called monocytosis.
There are two characteristics of monocytes: relative and absolute analysis. The relative increase in monocytes in the blood is based on the content of monocytes relative to the overall level of leukocyte cells. Normally, this value is 3-10%.The results of the medical analysis are recorded as “Mon #”.
The absolute content of monocytes in the blood is increased if the number of monocytes measured in cells per liter of blood is higher than normal. The absolute indicator does not depend on other blood cells, its rate for an adult man and a woman reaches 0.08 * 109 / liter. In the recording of the result of the analysis in monocytosis, monocytes abs.increased "or" Mon: number / l. "
When diagnosing, both factors matter, but doctors usually pay attention to elevated monocytes in the blood as a percentage, because the absolute fluctuation may be insignificant compared to other changes in the composition of the blood. Also, the total number of monocytes varies from stress, poisoning, depletion of the body.to contents ↑
Causes of increased monocytes in the blood
Usually, the result of the analysis of monocytes becomes only a confirmation of the diagnosis that has already been obtained, the first symptoms of which have already appeared. This is due to the fact that the production of monocytes in increased volumes takes some time, which is usually enough to spread the infection.
infections First of all, monocytes increase in response to an infectious disease. These include both seasonal colds and more severe complications: mononucleosis, rickettsiosis, endocarditis, tuberculosis, syphilis, and more.
Often, elevated levels of monocytes in the blood persist after recovery. In order to confirm this, you should pass the analysis again after a couple of weeks.
The second factor that causes an increase is cancer. Tumors are perceived by the body as foreign objects, so it is not surprising that with the help of monocytes, the immune system seeks to get rid of them.
- Autoimmune Diseases
The third reason monocytes are elevated in the blood is autoimmune diseases. When the immune system fails and it begins to perceive its cells as foreign, monocytes are produced on an enlarged scale. These diseases are very dangerous precisely because the body can destroy itself. These include lupus erythematosus and rheumatoid arthritis.
The fourth reason for the increase is surgery. Especially the number of these cells increases when it comes to the removal of the spleen, appendix, interventions in the "female" organs.
- Blood diseases
Finally, if monocytes in the blood are elevated in an adult, the cause is to be found in blood diseases.
Most often, the number of monocytes increases in conjunction with other blood cells. But even a complete blood count without a detailed examination can give an erroneous diagnosis. For example, the fact that lymphocytes and monocytes are elevated may indicate both the presence of a cold infection and leukemia, a malignant blood disease.
The fact that monocytes and eosinophils are elevated also indicates an enhanced immune system that is trying to cope with an unknown adversary:
The reasons why monocytes are elevated during pregnancy are no different from those listed above. However, an infectious disease identified in the future mother should be subjected to more attentive treatment in order not to damage the health of the future baby.
Elevated monocytes during pregnancy must be normalized, since otherwise birth can be complicated, there will be a risk of pathologies in the child and a threat to the mother’s health will be created.
In the event that monocytes are elevated in an adult, you must first establish the exact cause, and only then prescribe treatment. Getting rid of leukemia requires a lot of time, medicine and money, but this does not guarantee full recovery. Therefore, it is necessary to regularly donate blood for leukocyte and general analysis.
If you still have questions about how monocytes are elevated in the blood test, what it means, and what to do next, ask them in the comments.
God bless you!