What causes asthma in blood tests?
Aspartate amine transferase, AST, ASTaT, or AST in the blood test means the same term in medicine, meaning the content in the human body of an enzyme that is involved in protein metabolism and the breakdown of amino acids. This enzyme is part of many cell membranes and is found mainly in the spleen, heart, brain, liver, pancreas, and skeletal muscle. However, asth may not be active in all organs. Moreover, if asth is elevated, one can think of a rather limited circle of possible pathologies. As long as the structure and functions of the cells are not disturbed, and the organs in which asth is predominantly functioning fully in normal mode, the level of the enzyme in question in the blood stream will be minimal and not beyond the normal range. Excessive output of the asthma enzyme into the bloodstream, usually triggered by a violation of the integrity of the cells of an organ, as well as the pathological condition that develops in it.
- Blood asthma rate
- Causes of asthma increase in bloodarticle. to contents ↑
Norm of asth in blood
In order to evaluate the results obtained and the intensity in the asthma enzyme's blood plasma, you need to know how much it should be in a healthy person.
The reference values (norm) for asparatamine proliferation level differ slightly in men, women, and children. Here are the established boundaries of the indicator, measured in units per liter( U / l):
from birth to one year up to 58 U / l;
1-4 years- up to 50 U / l;
4-7 years - up to 48 U / l;
7-13 years old- up to 44 U / l;
14-18 years old- up to 39 U / l
males- no more than 41 U / l;
women - no more than 31 U / l.
It should be noted that minor deviations from the level are allowed in children at the time of active maturation, in pregnant women in the first trimesters of pregnancy, as well as in patients who are treated with drugs and intramuscular injections, which affect the liver and cause an increase in AST activity.
In other cases, if aspartate aminotransferase is elevated, the doctor may suspect the development of extremely serious diseases and pathological conditions.to contents ↑
Causes of asthma increase in blood
Ideally, in a healthy person, the activity of asthma enzyme in the blood should be low. If in the blood test, asth is increased by 5-10 times relative to certain norms, usually this situation is caused by the development of viral infections. Usually, the patient is offered several times to donate blood for a biochemical examination in order to rule out a false or temporary deviation. After all, there are cases when aspartate aminotransferase, asthma is elevated as a result of certain conditions, for example:
- after injury on the eve of skeletal muscle injury or injury;
- after getting burned;
- after suffering thermal shock;
- after poisoning with poisonous mushrooms.
If an increase in the enzyme is repeated, and is not associated with the above pathological conditions, it can signal serious diseases overtaken. Increased asthma in the bloodstream causes:
- Hepatitis( acute, chronic, viral);
- Injuries to the heart( closed or open type);
- Myocardial Infarction or acute heart failure;
- Severe angina pectoris attack;
- Cirrhosis, cancer, liver carcinoma;
- Liver damage by toxic or hepatotoxic poisons, for example.ethanol or carbon tetrachloride;
- Endogenous intoxication inside the body, resulting from infectious or purulent lesions of soft tissues and internal organs;
- Acute pancreatitis;
- Cholestasis( stagnation of bile), as well as initial biliary tract cancer;
- Destruction or necrosis of muscle tissue, myodystrophy, myositis, gangrene, etc.;
- Launched alcoholism, resulting in the death of liver cells.
If the asth blood test is elevated, what does this mean for a particular person, the doctor must decide, based on several methods of diagnosis and a thorough examination.
As a rule, in order to determine in which particular organ a violation or a lesion occurred, together with aspartate aminotransferase( ast or asat) determine the level of alanine aminotransferase( alt or alat).If in the blood test alt and asth are elevated, the causes are most likely rooted in the pathological processes occurring in the tissues in which they are present. The ratio of these two enzymes is the medical name of de Rytis coefficient. If this parameter is more than 1, then we are often talking about heart disease, in other cases talking about liver disorders. Normally, this coefficient should be in the range from 0.9 to 1.8, with a heart attack, it can increase 5 times, with hepatitis, on the contrary, it drops to 0.5-0.6.
Also, when diagnosing, together with intracellular enzymes, such an indicator as conjugated bilirubin can be investigated, which is elevated in viral and induced lesions, in cirrhosis, biliary obstruction, and chemical or alcohol poisoning. An increase in alt and asth in normal bilirubin, may be in latent forms of cirrhosis or liver failure, it all depends on how much the level of enzymes is increased. If alat and asat in the blood are less than 2 times higher than the maximum normative value, it is not identified as a dangerous pathological process, in this case, the patient is recommended only to conduct regular monitoring and analysis.
It should be clearly understood that the increase in alt and asth is not an independent disease, but only a consequence of it. Therefore, in order to lower enzymes, it is necessary to eliminate the causes of the increase in asat( asth) in the blood.
Take care of your health!