What does CPK in the blood test mean - norms and decoding

Creatine kinase is an enzyme found mainly in muscular and skeletal tissues, as well as in the brain and cardiac muscle. This substance performs a rather important and crucial function, which is to convert creatine with adenosine triphosphate into phosphocreatine molecules. These high-energy components, in turn, are actively involved in biological processes occurring in the human body.

Table of contents:
  • The need for analysis, its features
  • Features of the analysis
  • What data is considered normal?
  • CK MV

A CK blood test is not often prescribed by doctors because it is aimed at establishing the functioning of the patient’s muscles. As a rule, it is carried out after the physical traumas suffered by the patient, which have led to the development of serious ailments. If there is damage in the muscle fibers, a sharp jump in creatine phosphokinase occurs, which is detected during a clinical trial.

What does a blood test on CPK show, and does an increase in the level of this e

nzyme always indicate serious diseases? Every patient should know this.

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The need for analysis, its characteristics

A blood test for CPK is performed if the doctor, based on the patient's complaints, has good reason to believe that there is a serious pathology:

  • of the heart;
  • brain;
  • muscle;
  • heart vessels.

It is very important to understand what blood shows in CPK, and which indicators are not critical, and which ones indicate serious pathologies. Of course, it is not always a jump in the level of this enzyme to talk about diseases, but it is still impossible to ignore such a deviation.

Thus, a doctor may prescribe a blood test for creatine phosphokinase if there is a suspicion that the patient suffers from:

  • a pre-infarction condition or a developed myocardial infarction( a CPC MB study is being scheduled);
  • dermatomyositis;
  • muscular dystrophy;
  • the presence of inflammatory processes in muscle tissue;
  • polymyositis;
  • myositis viral etiology;
  • muscle injury;
  • GM malfunctions;
  • pre-stroke condition or stroke;
  • rheumatic heart disease;
  • arrhythmias;
  • TBI;
  • too intense physical exertion;
  • use of injectables administered directly into the heart muscle;
  • frequent attacks of tachycardia, etc.

Also analysis of the content of creatinophosphokinase in the blood is carried out to monitor the patient's condition during the postoperative period( if there was surgery on the heart, brain during TBI or other injuries, as well as in the muscle).

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Features of

analysis What is CPK in the biochemical analysis of blood, and what role does it play? The level of creatine kinase helps the attending physician to judge whether the above-mentioned pathologies occur, as well as whether the treatment gives the result to the patient. The study is conducted not only for the purpose of diagnosis, but also to track the positive dynamics after surgery, drug therapy, etc.

What is this diagnostic procedure - a CK blood test? Using a special technique, the level of this enzyme is determined and further interpretation of the data obtained by the attending physician is carried out.

Blood is taken from a vein from the inside of the elbow in the morning time of day. During the study, the blood is divided into a fraction and plasma. Calculus CPK in the biochemical analysis of blood is carried out in units of 1 liter of biological material.

Sometimes it may be necessary to retake the analysis. To avoid this, you need to prepare for the procedure correctly.

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What data is considered normal?

The rate of creatine phosphokinase depends on the sex and age of the patient, and indicators may vary slightly in pregnant women. The generally accepted optimal indicator is the level fluctuation within 20-200 U / liter.

There is such a thing as creatine kinase MV.Normal indicators of this enzyme differ from ordinary CPK, and the patient should be aware of this in order not to panic when receiving suspicious results of the study.

MV KFK is an enzyme that is responsible for the normal functioning of the heart. Analysis to determine its level is carried out in cases of suspected heart attack, stroke, coronary artery disease, etc.

The rate of creatine kinase in male patients can range from 52 to 200 U / L.

Creatine kinase in the blood of women normally ranges from 35 to 165 U / l of blood. During pregnancy, these figures may decrease slightly, so the patient who is expecting a child should not worry about this.

Blood CPK values ​​in newborn babies are significantly higher than those in adults. This is due to the fact that muscular and cardiac activity in babies is more intense. For this reason, the newborn baby CPK level can reach 652 U / l.

Over time, the level of this enzyme decreases, and by 5 days, the figures may drop to 295 U / l of blood. This level of CPK in a child is maintained until he reaches six months of age. After this, creatine kinase levels continue to slowly fall.

Thus, in babies from 6 months to a year, a rate of 203 units per liter of blood is considered the norm, and in babies from one year to 3 years, the most optimal CPK level is less than 228 U / l of blood.

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Norm KFK MV ranges from 0 to 24 U / l of blood. Any deviations from these indicators should cause serious concern, and cause for further diagnostic procedures to assess the work of the heart muscle.

When decoding analysis data on CFC MVs, inaccuracies can sometimes occur, so a patient can be re-examined. The level of this enzyme may increase and decrease from time to time, so the doctor cannot take steps to fully clarify the causes of this anomaly. Consider an example.

In myocardial infarction, CK MV in the blood can be 3-4 times higher than normal. Such a deviation can last for 4-8 hours after suffering an attack. The peak of enzyme activity is observed 4-12 hours after a heart attack. If this does not occur, and when deciphering CK MV, there is still a high activity of these enzymes, this may indicate necrosis of the heart tissues. Only in this case, the doctor can take emergency measures to prevent death. Prior to this, for one and a half days after a heart attack, medical workers can only observe the dynamics and activity of creatine kinase.

Note. The study of serum to determine the level of creatine phosphine kinase can sometimes give inaccurate results, which is a good reason for re-analysis. In order for the next indicators to be correct, it is necessary to exclude all factors that can affect them. If even after this the results remain the same, the patient is prescribed additional studies to make an accurate diagnosis.

Medication for cardiac pain or high blood pressure, steroid medications, alcohol tinctures, etc. may affect the level of CPK. Delays in the delivery of the biomaterial to the analysis may also have a negative effect on the accuracy of the data. For this reason, it is necessary to arrive at the clinic as early as possible so that blood can be taken before 11 am, and the specimen for the study is delivered to the laboratory for research.