Than to treat an intestine after radial therapy


Radiation of the intestine - Causes

Radiation disease or radiation damage to a number of organs, including the intestine, develops with the use of nuclear weapons (the tragedy in Hiroshima and Nagasaki in 1945), violation rules of safety and negligence with sources of ionizing radiation (events at the Chernobyl nuclear power plant), irrational appointment of large doses of radiation therapy. With local irradiation of the abdominal and pelvic organs, the total dose of which exceeds 40 Gy (4000 rad), pathological changes can develop, mainly in the intestine. Most often, the defeat of the small and large intestine is combined, although there is often an isolated process in one of these parts of the intestine.

The first clinical report on bowel damage after radiotherapy of malignant neoplasm was made in 1917. TO. Franz and J. Orth. As the scope of radiotherapy has expanded, the number of reports of its complications has increased. In particular, it was noted that irradiation of various pelvic, intraperitoneal

and retroperitoneal neoplasms leads to the appearance of radiation enteritis and colitis in 5-15% of patients. According to D. L Earnest, J. S. Trier (1983), radiation damage to the gastrointestinal tract continues to be one of the main and serious clinical problems.

The mechanism of the appearance of intestinal injuries under the action of ionizing radiation is primarily its effect on the epithelium of the mucous membrane, which is very sensitive to radiation exposure. Irradiation promotes suppression of cell proliferation in crypts, which causes characteristic acute disorders. If the radiation dose is low, the proliferation of epithelial cells is restored fairly quickly, and mucosal damage disappears 1-2 weeks after irradiation. The effect of repeated doses of radiation depends on the duration of irradiation and the stage of cellular renewal of the crypt epithelium. It has been established that the epithelial cells are particularly radiosensitive in the G1-postmitotic phase and resistant to the late S-synthetic phase. To restore the regeneration of the epithelium of the intestinal mucosa during fractional irradiation, the duration of the intervals between exposures is of great importance.

As can be seen, the development of acute and chronic changes inherent in radiation enteritis is affected not only by the total dose of irradiation and the method of its use, but also by the time between the courses of therapy.

Radiation therapy before and most often affects the epithelium. It also has an effect on mesenchymal tissue, which is most important in the occurrence of long-term effects. For example, the endothelium of the small intestine submucosal arterioles is very sensitive to the effects of ionizing radiation and reacts to large doses by proliferation. Vascular disorders appear after 1 week or 1 month after acute damage to the mucosa. The wall of the vessels undergoes fibrinoid changes, which further facilitates the thrombosis of the vessels. Develop obliterating endarteritis, endophlebitis, leading to ischemic disorders of the intestinal wall, followed by ulceration and necrosis. It worsens the patient's condition and aggravates the damage to the intestinal wall by introducing bacteria into the necrotic tissue, which increases as the blood supply deteriorates.

After massive irradiation, the gut becomes swollen; activation of fibroblasts is noted, connective tissue undergoes hyalinosis, in the development of which smooth muscle cells participate. As a result, extensive fibrosis is formed, which can lead to a narrowing of the intestine, as well as to destruction of the mucosal surface. Consequently, ionizing radiation can cause both transient changes in the structure of the mucosa and bowel function, as well as thickening, ulceration, and intestinal fibrosis.

In addition to acute and chronic changes in it, subacute and latent are distinguished. Acute - occur immediately after irradiation, accompanied by a violation of proliferation and maturation of the epithelium in combination with a decrease in the mitosis of crypt cells. In the small intestine, characteristic shortening of the villi and a decrease in the thickness of the mucosa, as well as its hyperemia, edema and extensive inflammatory cell infiltration are observed. Crypt abscesses that contain neutrophils, eosinophils, and deleted epithelial cells are possible. With prolonged or massive irradiation, ulceration may occur.

Subacute changes appear 2 to 12 months after radiation therapy. They are very diverse. During this period, the endothelial cells of the small intestine arterioles in the submucosa can swell, flake off the basal membrane and eventually undergo necrosis. In the lumen of the vessel, thrombi are detected, in some cases, their recanalization. In the intima, large foam cells are found, which, according to some researchers, are considered to be an important diagnostic sign of radiation damage to blood vessels in humans. The submucosal layer becomes thickened, sclerosed, often contains large, irregularly shaped fibroblasts. The result of obliterating changes in small arterioles is progressive ischemia. The degree of vascular lesions and ischemic fibrosis is different and not always pronounced, therefore in the subacute the blood circulation in the intestine is often not significantly disturbed, except for cases when irradiation was preceded by diseases that affected the vessels (hypertension, diabetes, generalized atherosclerosis or coronary and cardiac failure). Insufficiency of microcirculation due to radial vasculitis, representing the greatest danger, often occurs in the sigmoid and rectum. In the tissues that connect the large intestine with the vagina, bladder, ileum, abscesses and fistulas may form. Gut carcinoma is a late and relatively rare manifestation of its radiation damage.

After radiation therapy

Despite the fact that a couple of months after the procedures of radiotherapy, the condition of patients is not bad, a number of patients feel weakness, sweating, and lowering of pressure.

Also, in almost all patients, skin burns are recorded # 8212; thissigns of radiation sickness. Although they can manifest themselves in different degrees.

In most cases, side effects and complications after radiation therapy pass independently, but often the recovery takes a long time, where it takes about six months.

To accelerate the process of body regeneration after radiation therapy, it is acceptable to apply the prescriptions of folk medicine.

Folk remedies after therapy

To exit the state of exhaustion after radiotherapy, take a hundred grams of dried St. John's wort, chamomile, birch kidney and immortelle, mix and grind. The mixture is placed in a glass or ceramic container and tightly closed with a lid. After dinner, brew a tablespoon of mixture half a liter of boiling water, and use a glass of tea leaves with a teaspoon of honey. At night you can not drink. Before breakfast (for twenty minutes), heat the rest of the tea leaves and re-use it with honey. The course lasts until the end of the collection stock. You can repeat treatment in two years.

Mix in equal quantities birch buds, immortelle, angelica root, oregano, nettle, St. John's wort, linden color, mother-and-stepmother, mint, plantain, dandelion root, motherwort, pine buds, chamomile, yarrow, sage, celandine, thyme. Select fourteen tablespoons of the mixture and pour three liters of boiling water. The tea leaves are tightly closed and wrapped. After eight hours, filter. Store in a cool place for not more than five days. Take the first glass between breakfast and lunch, and the second between lunch and dinner. This is a vitaminized cleansing collection, it relieves the body of harmful substances accumulated during radiation therapy.

Complications after radiation therapy

Radiation therapy radiationinteracts not only with the tumor, but also with neighboring tissues, hence complications arise in the form of radiation injuries. These defects can develop up to three months or more after the end of treatment and their quantity is approximately 10%. These complications include dermatitis with telangiectasia, radiation edema, radiation ulcer and similar injuries. And all these complications need serious baking. Good results are provided by surgical excision of damaged tissues with plastic replacement of the defect.

To mitigate the effects of rays on the skin, you need after the procedures to lubricate the areas of irradiation with aloe emulsion, pork fat, olive or sea-buckthorn oil, or rosehip oil. Children's and Velvet creams are also used. Keep these areas of the skin open. For a week and a half before the start of treatment it is forbidden to use tincture of iodine and ointments that include mercury or sulfur in the composition.

Physical exercises

You can not neglect the practice of therapeutic gymnastics and autogenic training, a positive result from these exercises is seen. At the same time, mental balance, resilience and self-reliance are restored.


Do not be discouraged, noticing for yourself irritability, worldwide grief and tearfulness. These are all the reactions of the body to radiation therapy. In such cases, you need to overcome yourself and it's good that you have a good "support group". Do what you enjoy, and breathe more often with fresh air.

The most responsible and effective period after recovery # 8212; the first couple of years. This is very important courses of general strengthening therapy and sanatorium treatment.

After treatment, be sure to undergo regular preventive examinations from the doctor who supervises you.

The most interesting news

Side effects of radiation therapy for intestinal tumors

Patients with diagnosed tumors of the rectum, thick and small intestines very quickly fall on the operating table. Before that, they can go for years on doctors of various professions with complaints of eructations, bloating, gases, constipation or constipation, alternating with diarrhea, frequent urge in defecation, without emptying a straight line guts. Doctors very often diagnose: intestinal dysbacteriosis, chronic gastroenterocolitis, atony intestines, etc. The diagnosis of cancer is established only after the appearance of blood in the bowel movement or from the direct guts. Doctors conduct X-ray examination with contrast material, colonoscopy or digital examination of the rectum.

In oncology, there is a setting: when diagnosing cancer after puncture a tumor for histological examination, the patient is given an operation or irradiation for eight days. For the patient, this happens so swiftly that he does not have time to "come to himself" during these days and, perhaps, to consult someone else, to consult - there is already no time.

Preoperative irradiation of a cancerous tumor is carried out with the capture of the underlying, healthy tissues, resulting in their death and decay. Therefore, in the postoperative period, good tissue healing does not always happen. In 90% of cases, these patients develop purulent, long-term healing fistulas.

If the patient has a different type of fungus, then the treatment with antibiotics penicillin series will only aggravate the treatment process. Fungal mycelia, preserved in the underlying tissues, only receive stimulation from preparations prepared from mold fungi (penicillin). In addition, as a result of irradiation, excellent conditions are created for germination of fungi to nearby organs. For example, irradiated mycelial fungus and Trichomonas becoming more aggressive, begin to "devour" weakened by radiation healthy cells.

Cancer cells after irradiation become a source of secondary radiation, dangerous for vital organs. Irradiation of a cancerous tumor contributes to the weakening of immunity, the development of additional infection and the formation of purulent and fistulous processes. Irradiation of a cancerous tumor stimulates its spread from the primary source through the circulatory system - metastasis. Preliminary irradiation of a cancerous tumor of the rectum before the operation can cause the spread of metastases to the liver and lungs. The tumor itself, which was directed to gamma-irradiation, in most cases decreases in size, but only due to the decay of more preserved, albeit altered cells of the rectum in the structure of the tumor, and in the underlying tissue, as well as by reducing edema. In the case of the presence of fungi in the body of the patient, for example: mycelium mucora racemisus, Trichomonas and chlamydia, not only do not destroy, but on the contrary, are doping to growth and reproduction. Through the destruction of the blood vessels of the rectum, the fungal mycelium additionally enter the blood, depending on the anatomical features of the intestinal circulation.

The portal vein goes to the liver and, branching, is located between the lobules of the liver, where the mycelial fungus and Trichomonas with Chlamydiae are deposited. So, with the location of a cancerous tumor in the middle and upper parts of the rectum, it gives metastasis to the liver.

The lower venous network of the rectum directly flows into the hollow vein and blood, bypassing the liver, through the right divisions the heart passes into the numerous venous network of the lungs, where the mycelial fungus and Trichomonas with chlamydia settle. Consequently, with the location of a cancerous tumor in the middle-lower and lower parts of the rectum, distant metastasis will occur in the lungs.

Based on clinical experience, already 3 to 4 weeks after irradiation (gamma therapy) of rectal cancer, metastases may appear in the liver, duodenum and pancreas.

Physicists have established the presence of slow neutrons over any part of the earth's surface. Connecting in the human body with the atoms of sodium, calcium, magnesium, phosphorus, iodine, they make them radioactive. Microbiologists have established that fungi primarily absorb radioactive elements. It is not for nothing that mushrooms in the forest are called "forest orderlies". Radioactive fungi in the body lead to the ionization of its cells. Studies of microbiologists have shown that dried malignant tumors are more radioactive than dried healthy tissues. If the radioactivity is extinguished, the tumor will cease to grow, and then dissolve. This is another proof of the fungal structure of the cancer. Perhaps in this lies the mystery of a family defeat of cancer, if family members are in constant contact with a relative - a carrier of radiation. In 10% of cases, cancer occurs in married couples (husband-wife). The hereditary factor is found in 70% of cases (from an anamnesis and on indicators of hereditary DNA damage). Who has more fungi in the body, he is more sensitive to radiation. The presence of fungus in the body leads to a rapid development of a cancerous tumor. From scientific microbiological studies it is known that when radiation is irradiated with mycelium, spores of fungi become accumulators and sources of secondary radiation. Their distribution after irradiation through the circulatory system from the upper parts of the rectum goes to the liver, and from the liver to the duodenum gut, from the duodenum - into the pancreas, affecting the organs not only with fungal, trichomonas and other infections, but also radiation. From the mid-lower divisions of the rectum, radioactive mycelia with blood flow along the vena cava are directed to the heart. And, as we see, the patient is diagnosed with radioactive damage to the heart tissue (in general, and the pericardium).

We can conclude:Irradiation of the cancer stimulates its spread - germination in the nearby organs, and also contributes to the weakening of immunity, the development of additional infection and the formation of festering and fistulous processes.



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