But the spine with spasms in the intestine


About pain and spasms

More on pain and spasms

The term pain has two definitions: it is a kind of psychophysiological state that arises as a result effects of superstrong or destructive stimuli, causing organic or functional disturbances in organism. In a narrower sense, pain (dolor) is a subjectively painful sensation resulting from the action of these superstrong stimuli.

Pain is an integrative function of the body, mobilizing different functional systems to protect against the impact of the harmful factor [4]. Conditionally, two basic types of pain are distinguished in man: nociceptive, which arises when specialized pain receptors - nociceptors, and neuropathic, developing with damage to the endings of sensory nerves fibers. High-threshold mechanoreceptors are activated by excessive reduction and spasm of hollow organs, forming acute pain. This type of receptor is common in the heart, esophagus, bronchi, bile duct, small and large intestine, ureters, bladder and uterus [2].

Spasm is a sudden, involuntary c

ontraction of muscle or muscle group [1]. Muscle tension in pain syndromes is, on the one hand, a protective reflex, and on the other hand, a pathological mechanism of chronic pain (3).

Cure for pain and spasms

Feeling pain, a person by tradition takes an anesthetic, which can often mask the pain and, as a consequence, make it difficult to diagnose.Spasmolytics, on the contrary, are eliminated from the main causes of abdominal pain - a spasm of smooth muscles.Many of them are allowed for over-the-counter vacation. Such drugs include No-Shpa tablets.

The drug No-Shpa - a tool with a half-century history, used for smooth-muscle spasms and pain. It helps with spasms of smooth muscles of the intestine, gall bladder, as well as in painful menstruation caused by a spasm of smooth muscles [6]. Due to the mild vasodilating effect, the No-Shpa tablets improve the blood supply to the tissues [5].

But-spa of pain and spasms

But-Shpa in tablet form is used in clinical practice in many countries of the world and is used by doctors of different specialties:

  • gastroenterologists,
  • urologists,
  • obstetrician-gynecologists.

ATgastroenterologyBut-Shpa in tablets is prescribed to eliminate the pain syndrome caused by a spasm of smooth muscles in diseases of the bile ducts: 1) cholecystitis, 2) cholangitis, 3) cholelithiasis. Together with other drugs, No-Shpa is prescribed to eliminate spasms of smooth muscles with peptic ulcer and duodenal ulcer guts, gastritis, with spasms of cardia and pylorus, enteritis, colitis, spastic colitis with constipation, irritable bowel syndrome with flatulence [6] .

ATurologyNo-Shpa tablets are used to relieve spasmodic pain in various diseases, such as: nephrolithiasis, urethrolithiasis, pyelitis, cystitis, and bladder cramps [6].

ATgynecologyNo-shpa tablets are traditionally used to arrest spasm in the complex therapy of dysmenorrhea - pathological process, in which in the days of menstruation there are severe pains in the lower abdomen (algomenorea) [,].

Also, No-Shpa tablets are also used for complex treatment of tension headaches. when the main cause of the painful condition is the involuntary tension of the cranial (frontal, temporal, occipital) and trapezius muscles [,].

A good balance of efficiency and time-tested safety allowed the attribution of No-Shpa tablets to OTC drugs [6].

  • [1] The American Heritage® Medical Dictionary Copyright © 2007
  • [2] Baranskaya E. TO. Abdominal pain: clinical approach to the patient and treatment algorithm. Place of spasmolytic therapy in the treatment of abdominal pain // Pharmateka.-2005.-No. 14 (109) // Pharmateka. - 2005. - No. 14. - FROM. 109
  • [3] Barinov A. N. Segmental mechanisms of the formation of muscle spasm, spasticity and chronic pain / / Phys. -. - T. 5. - FROM. 17-23.
  • [4] A. Bronshtein Rivkin V.L. Study and treatment of pain (a review of the literature and statement of problems) // International Medical Journal. - 2001. - No. 3. - FROM. 267-271.
  • [5] GM Jobava Mandrykina Zh.A. Loginova K.B. Dobrokhotova Yu.E. Dysmenorrhea. Etiopathogenesis, differential diagnosis and therapy in the practice of modern obstetrician-gynecologist. // [Electronic resource] of breast cancer; 1. URL: http://www.rmj.ru/articles_8098.htm
  • [6] Instruction on the medical use of the drug No-shpa 40 mg (tablets) reg.уд. П N011854 / 02
  • [7] Rybak V.A. Miroshnikova V.V. Babushkin Ya. Kh. Tension headache. Medicinal Herald. 2006; 4-9
  • But-spa - Instructions

    Dosage form:

    capsules, solution for injection, tablets, coated tablets

    Pharmachologic effect:

    But-spa-myotropic antispasmodic. The chemical structure and pharmacological properties are close to papaverine, but it has a stronger and longer action. Reduces the flow of Ca2 + into smooth muscle cells (inhibits PDE, leads to the accumulation of intracellular cAMP). Reduces the tone of the smooth muscles of internal organs and intestinal motility, dilates the blood vessels. Does not affect the autonomic nervous system, does not penetrate the central nervous system. The presence of a direct effect on smooth muscles can be used as an antispasmodic in cases, when drugs from a group of m-holinoblockers are contraindicated (closed-angle glaucoma, hypertrophy of the prostate glands). With IV introduction, the effect begins - after 2-4 minutes, the maximum effect develops in 30 minutes.


    Prevention and treatment: spasm of smooth muscles of internal organs (renal colic, biliary colic, intestinal colic, dyskinesia of biliary tract and biliary tract bladder hyperkinetic type, cholecystitis, postcholecystectomy syndrome); pyelitis; spastic constipation, spastic colitis, proctitis, tenesmus; pilorospazm, gastroduodenitis, peptic ulcer of stomach and duodenum (in the phase of exacerbation, as part of complex therapy - to relieve the pain syndrome of spastic character). Endarteritis, spasm of peripheral, cerebral and coronary arteries. Algodismenorea, threatening miscarriage, threatening premature birth; spasm of the throat of the uterus during labor, prolonged opening of the throat, postnatal fights. In carrying out some instrumental studies, cholecystography.


    Hypersensitivity, marked hepatic and renal insufficiency; CHF, AV blockade II-III st. cardiogenic shock, hypotension. With caution. Pronounced atherosclerosis of the coronary arteries, angle-closure glaucoma, prostatic hyperplasia, lactation period, pregnancy (I trimester).

    Side effects:

    Dizziness, palpitations, a feeling of heat, increased sweating, decreased blood pressure, allergic skin reactions. With / in the introduction - collapse, AV blockade, arrhythmia, oppression of the respiratory center. Overdose. Symptoms: in large doses No-shpa violates atrioventricular conduction, reduces the excitability of the heart muscle, can cause heart failure and respiratory center paralysis.

    Dosing and Administration:

    But-shpa take inside, adults - 40-80 mg 3 times a day; in / m, p / c - 40-80 mg 1-3 times a day. For relief of hepatic and renal colic - IV, slowly, 40-80 mg. With spasms of peripheral vessels, the drug can be administered in / a. Children under the age of 6 years - in a single dose of 10-20 mg, the maximum daily dose - 120 mg; 6-12 years single dose - 20 mg, maximum daily dose - 200 mg; multiplicity of appointment - 1-2 times a day.

    Special instructions:

    In the treatment of gastric ulcer and duodenal ulcer, No-shpa is used in combination with others. antiulcer drugs. During the treatment period it is necessary to refrain from driving motor vehicles and other activities. potentially dangerous activities requiring increased concentration of attention and speed of psychomotor reactions (within 1 h after parenteral, especially in / in the administration).


    With the simultaneous use of drotaverine can weaken the antiparkinsonian effect of levodopa. Strengthens the action of papaverine, bendazole, etc. antispasmodics (including m-holinoblokatorov), a decrease in blood pressure, caused by tricyclic antidepressants, quinidine and procainamide. Phenobarbital increases the severity of spasmolytic action of drotaverine. Reduces the spasmogenic activity of morphine.

    Before using the drugBut-shpaconsult with your doctor!

    28.03.2010 / 0: 0

    you can take no-shpu with such drugs, ak Mycosyst. and are there any medicines that can not be taken? Thank you)

    30.03.2010 / 1: 2

    Interaction: Strengthens (especially with iv introduction) the effect of others. antispasmodics (including m-holinoblokatorov), hypotension caused by tricyclic antidepressants, quinidine, novocainamide. Reliability of spasm elimination increases phenobarbital. Reduces spasmogenic activity of morphine, antiparkinsonian properties of levodopa. Special instructions Caution should be used when prescribing a patient with severe atherosclerosis of the coronary arteries. But-shpa can be used as a part of combined therapy for relief of hypertensive crisis. In the treatment of peptic ulcer of the stomach and duodenum, No-shpu is used in combination with anticholinergics. Drug Interactions With simultaneous application of No-shpa forte can weaken the antiparkinsonian effect of levodopa. With the simultaneous use of No-shpa forte enhances the effects of papaverine, bendazole and other antispasmodics (including m-holinoblokatorov). With the simultaneous application of the triadic antidepressants, quinidine and procainamide to the forte with forte, hypotensive effect is enhanced. With simultaneous application of No-shpa forte reduces the spasmogenic activity of morphine. With the simultaneous use of phenobarbital increases the severity of spasmolytic effects of drotaverine. http://www.tiensmed.ru/news/noshpa-wkti/.

    02.04.2010 / 2: 1

    Well, for example, spasms in the abdomen, if they are from the gastrointestinal tract, but-shpa almost does not remove, well, or you need to drink a handful of no-shpy. Already so many people said it. I know, her pregnant woman is pregnant with a threat of miscarriage, and with pain in her stomach buy better Duspatalin. without options, and that's the list of side effects and interactions that he does not have. But more effective.

    Got you a pain in the intestine so that you can not stand straight, drank a snipe and after five minutes it will be lifted by hand.
    But when algodismenorei I do not feel it, I prefer a stronger type of Nize.

    But-spa is a popular treatment for many diseases. For oral administration, it is available in tablets that are suitable for use for 5 years from the date of manufacture.

    Mechanism of action.But-shpa # 8212; it is an antispasmodic, i.e., a drug that can eliminate spasms in the gastrointestinal tract, urinary tract, uterus and circulatory system. In this regard, the drug is able to improve the blood supply of ischemic organs, lower blood pressure, eliminate pain when spasms of the stomach, intestines, biliary and urinary tract, to maintain pregnancy with a premature increase in the tone of the uterus and the threat of miscarriage. By its action in the body no-sppa is similar to papaverine, but it has a stronger and prolonged spasmolytic effect. Just like papaverine, but-shpa begins to show its effect through 20 # 8212; 30 minutes after ingestion. Caused by a single reception of no-spasm antispasmodic effect persists about 5 # 8212; 6 hours.

    Application.But-shpa is used for colic caused by spasms of various parts of the gastrointestinal tract (stomach, intestines, bile ducts), urinary system, as well as spastic constipation and pain caused by exacerbation of gastric ulcer and duodenal ulcer guts. In addition, no-shpa can be used to lower the blood pressure in hypertension (hypertensive crisis) or for improvement of blood supply to ischemic areas of the body with spasms of blood vessels (in particular, with obliterating endarteritis, angina pectoris, migraine). For the above indications no-shpa is used inside by 1 # 8212; 2 tablets 2 # 8212; 3 times a day. To achieve an earlier effect, the medicine can be taken under the tongue.

    Complications.But-shpa usually does not cause complications, however, when hypotension, taking the drug is undesirable, since it can even more lower blood pressure, and this can lead to collapse and the need for emergency care in connection with this.

    Contraindications.The drug is contraindicated in the case of collapsoid states (at very low arterial pressure), and also with an allergic reaction to the reception of no-shpa or medications containing this drug (nikoshpan, bishpan).

    Comments (2)

    Many people are prejudiced against anesthetics, but in vain. You just need to study the composition of the drug and instructions for use. Indeed, there are medicines that are better to abstain from, and there are those that will help you on days of PMS and menstruation. I drink Junipaz, he is good at relieving pain that negatively affects the body and should not be tolerated. This drug consists of paracetamol and drotaverine, it works perfectly.

    Has bought or purchased tablets Yunispaz N, in the leaflet-pouch it is written that it is possible to accept to children from 6 years old # 8212; it's almost safe spasmoanalgic. Pain from monthly was removed within an hour, almost all day. The medicine helped, I will use.

    Sources: http://no-spa.ru/no-shpa-ot-boli/, http://best-doctors.ru/prepara? d = 8928cl = all, http://lekaru.ru/populyarnye-lekarstva/no-shpa/


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