Poikilocytosis

Poikilocytosis is a blood condition or disease in which the form of red blood cells is modified or deformed to one degree or another. Red blood cells are responsible for the transformation of oxygen in every cell of our body and any deviation from the norm leads to a violation of their main function and overall health. It is difficult for an ordinary person without medical education to understand what this pathological process is connected with. Poikilocytosis, what it is, how to detect it and what we may face in more detail.

How to detect poikilocytosis in the general analysis of blood?

To identify any irregularities in the blood, it is sufficient to pass a normal general blood test at any clinic or collection point. To decipher the results, it is better to contact the appropriate specialist, for example, the local physician, especially if the concept of hypochromia, anizacytosis, poikilocytosis is present in the laboratory's conclusion.

Hypochromia is a low hemoglobin content in red blood cells.

Anisocytosis is a different size, form of red blood cells. The initial stage of anemia.

Poikilocytosis is the most unfavorable symptom of the above, indicating a change in red blood cells and indicating ongoing anemia in the moderate to severe stage.

Analysis will also show the amount of transformed red blood cells in the circulatory system of different shape. If poikilocytosis of erythrocytes is detected, he is assigned 1 of 4 degrees:

  • 1( +) Insignificant poikilocytosis. The number of "wrong" red blood cells does not exceed 25%.
  • 2( ++) Poikilocytosis in moderate to moderate degrees. Pathological red blood cells in the amount of about 50%.
  • 3( +++) Explicit poikilocytosis. The content in the blood of deformed erythrocytes reaches 75%.
  • 4( ++++) Acute Poikilocytosis. All 100% of erythrocytes are changed, rejected from the norm, differ from healthy ones.

In which diseases poikilocytosis occurs?

Depending on the shape of the erythrocytes, it is possible to determine which disease is referred to. The main types of forms and connection with this or that disease:

  • Acantocytes. The protruded erythrocyte spur cells are located at different distances from each other. Observed with liver diseases( eg, hepatitis, cirrhosis).
  • Dacryocytes. The shape of the cells resembles a drop. They indicate a weakening of bone marrow function, an acute deficiency of iron in the body, or toxic hepatitis.
  • Ovalocytes. Elongated cells of various oval shapes. The predominance of such erythrocytes may indicate hereditary anemia or ellipocytosis.
  • Echinocytes. Rounded cage with various protrusions or spikes. Occurs in patients with gastric cancer, or with acute disorders of the kidneys.
  • Drepanocytes. Cells resembling a sickle or moon, they contain hemoglobin S. The content of this type of red blood cells is threatened by an acute lack of oxygen in the blood and in membrane distortion.
  • Codocytes. Cells resembling a target, where the concentration of hemoglobin in the center. May be present with jaundice or lead poisoning.

To date, a large number of poikilocytosis is isolated in medicine.

Most people( about 80%) who have poikitlocytosis are found to have causes related to an acute shortage of iron and its deficiency in the body, which, in turn, greatly reduces hemoglobin. To bring blood cells to normal in this case, you need to start taking iron supplements. What is poikilocytosis in the blood test, what is its stage, what treatment of poikilocytosis or therapy you need to go through in order to answer all these questions, you need to take the necessary blood tests and consult with your doctor. Although poikilocytosis and anisocytosis are characteristic of the development of anemia in a person( or anemia in the common people), it is not a secret that any disease is easier to be cured at an early stage, therefore, for prophylactic purposes from time to time, take a complete blood count. Keep track of your hemoglobin, stay healthy!