Tetraiodothyronine is free in women: what is it responsible for, what is the rate and causes of deviations?
St. T4 in women is a hormone produced by the cells of the thyroid gland, which is an important part of the endocrine system. The first visit to a specialist specialist - endocrinologist - always begins with the patient receiving directions for 3 biochemical blood tests: TSH, T3( triiodothyronine) and T4( tetraiodothyronine, or thyroxin).
- T4 functions
- Norm of tetraiodothyronine in women
- Norm in pregnant women
- Causes of deviation from the norm. What exactly can tell the serum on T4?And for what processes in the female body is this substance responsible? Every woman should know this. to contents ↑
What is T4 hormone in women responsible for? This question is often asked by patients who first came to an endocrinologist's consultation. And it is not unreasonable, because we all know that hormones are very fragile and, at the same time, an important component that plays a huge role in the work of the whole organism.
Tetraiodothyronine is a hormone responsible for the metabolic process, both in the female and in the male and child's body. While the person feels well, there is nothing to worry about, but if alarming symptoms occur( they will be briefly discussed later), this becomes a reason for visiting the doctor.
So, what is thyroxin free in women? This substance is responsible not only for the metabolism, but also for:
- functioning of the central nervous system;
- carbohydrate and lipid metabolism;
- reproductive function( abnormality of the T4 free hormone in women can lead to a failure in the menstrual cycle, up to amenorrhea);
- heart work;
- production and absorption of vitamin A by the liver;
- excretion of excess cholesterol;
- bone metabolism stimulation;
- oxygen transport to the cells of the whole organism;
- normalization of heat metabolism.
Having understood that this is the hormone T4 in women, it is necessary to consider in more detail which indicators of this substance are the most optimal, including for future mothers.to contents ↑
Norm of tetraiodothyronine in women
The norm of the hormone thyroxine in women is slightly different from that in men, due to the structure and functioning of the female body. But it should be immediately noted that far from always deviations from generally accepted indicators are cause for concern. In any case, there is no need to worry about this before a blood test.
The rate of t4 free in women is measured in special units - picomoles, but it is also possible to measure in micromol( µmol) per liter of blood. It all depends on the clinic where the analysis is performed.
When performing the study, blood time is taken into account. It is known that in the morning the concentration of this substance is much higher than in the evening. At the same time, tetraiodothyronine level reaches its peak throughout the time period from 8 am to 12 pm. Its very minimum values are observed at night( until 4 am).
Note. The rate of the hormone T4 free in women depends on age. This takes into account the work of the reproductive organs. Given this, the level of thyroxin in patients during menopause increases significantly, which is not a deviation.
If the test results for T4 are normal free( for women), they will be as shown in the table( in units of µmol).
Age category Norm indicators( µmol) From 18 to 50 years In the range of 0.9 - 11.8 In 50-60 years 0.7 - 0.5 From 60 to 70 years In the range 0,4 to 3.5 In women over 70 years of age 0.5 - 2.4
For the norm and role of the hormone T3 in a woman's body, see http: //vseproanalizy.ru/ t3-svobodniy-u-zhenshhin.html
In whatever units tetraiodothyronine is not measured in women, only the endocrinologist should deal with the interpretation of the results of the study. He also makes a decision about the appropriateness of the course of treatment if T4 deviates from the above indicators.to contents ↑
Norm in pregnant women
Norm T4 free during pregnancy depends on the period. This substance is important not only for the mother, but also for her future baby. With a deficiency of tetraiodothyronine in the blood, the formation of the fetus and its physical and mental development slows down significantly, which can have adverse consequences after the birth of the child.
- Norm T4 free during pregnancy in the first trimester can vary from 12 to 19 pmol. This is quite sufficient for the mother to feel quite normal, and the embryo developed fully, without any anomalies.
- In the 2nd trimester it is slightly lower, and is 9.6 - 17 pmol / l. This decrease is due to fetal growth, and this process requires more energy from my mother's body.
- In trimester 3, it is even lower, since, although the child is almost fully formed( at 7-8 months), he still needs to receive energy from his mother's body. During this period of time, the level of thyroxin can fluctuate between the values of 8.4 - 15.6 pmol, which depends on the month( 7-9) of pregnancy, the size of the fetus and the individual characteristics of the organism of the future mother.
As can be seen, T4 free in pregnant women has the highest results in the first trimester, and as the fetus grows, the concentration of the substance, on the contrary, decreases. This is absolutely normal, moreover, after delivery, tetraiodothyronine levels will gradually return to normal, especially if the woman decided to give preference to breastfeeding the newborn baby.
Note. If during pregnancy T4 free significantly exceeds the norm, this may indicate the development of thyrotoxicosis. Alas, expectant mothers are not a rare phenomenon, and although it is not dangerous for the health of the mother and the unborn child, yet this condition requires increased attention from the doctor.to contents ↑
Causes of abnormality
What is this analysis for T4 in women? A clinical study of blood serum helps to identify an increased or decreased level of thyroxin, and determine the causes of deviations.
An increase in tetraiodothyronine concentration may be associated with:
- excessively intense bilirubin production by the body;
- development of toxic goiter;
- chorionic carcinoma;
- by different types of thyroiditis;
- chronic liver disease;
- formation of adenoma in thyroid tissue;
- development of nephrotic syndrome;
- postpartum thyroid dysfunction;
- taking certain groups of drugs.
With an elevated level of thyroxine, a woman becomes irritable, hot-tempered, she is tormented by tachycardia, sleep disturbances, and bouts of arrhythmia. Similar symptoms should not be ignored, therefore consultation of the endocrinologist is obligatory.
The reasons for the increase in T3 free are given on the link http: //vseproanalizy.ru/ t3-svobodnyoj-povyshen.html
What this T3 reduction says here.
Reduced T4 level can be caused by:
- recently transferred operations( in particular, in the SHZ);
- dramatic weight loss;
- diseases of the hypothalamic-pituitary system;
- long-term use of hormonal contraception;
- postponed TBI;
- deficiency of iodine and others.
With a deficiency of thyroxin, the patient becomes whiny, apathetic. They have fatigue, fatigue, and general weakness. They complain of the presence of swelling of the face and limbs, deterioration of hair, brittle nails and cracking of the skin. There is a significant gain in weight.
It should be remembered that without finding out the causes and proper treatment, the deficiency or excess of tetraiodothyronine will not disappear. After passing the diagnosis, the doctor will choose the optimal method of therapy, which will help get rid of the existing problem without harm and consequences for women's health.