What functions does the T3 free, its rate and causes of deviations?
T3 or triiodothyronine free - what is this hormone? Whole groups of different hormones take part in the functioning of the human body, each of which is responsible for the operation of certain systems. Thus, progesterone and estrogen normalize the functions of the sexual sphere, adrenaline prevents the development of shock in an extreme and stressful situation, and also contributes to the full activity of the heart muscle, but the free hormone T3 is responsible for the thyroid gland, liver and kidneys. Of course, the level of this substance depends on the work of all systems, but it is these organs that produce it in maximum quantities.
- The main functions of triiodothyronine
- What is T3 responsible for?
- Norm triiodothyronine in the blood test for T3
- When prescribed for triiodothyronine
- What test should be taken?
- Deviations from the norm of triiodothyronine
- Increased T3
- Drop in T3
With an increased or, conversely, low concentration of this substance, a malfunction of the internal organs occurs. And since jokes with hormones are bad, everyone needs to act immediately, so everyone should be aware of what the specific T3 hormone is responsible for, and what its rate is.
The main functions of triiodothyronine
First, let's understand what it is free T3, what functions it performs and where it is produced.
human thyroid gland produces the synthesis of such essential hormones as triiodothyronine( or T3) and thyroxin( hormone T4).When the second decays, one iodine element is simply separated, as a result of which a new hormonal compound, triiodothyronine, is formed. Therefore, if we consider the question of what T3 is, then we can say that this is a specific substance, which is a derivative of the hormone T4.
For details on the role of the hormone T3 in the female body, see http: //vseproanalizy.ru/ t3-svobodniy-u-zhenshhin.htmlto contents ог
What is T3 responsible for?
Since this substance plays an important role in the functioning of the thyroid, it is necessary to know about the functions of triiodothyronine. So, it contributes:
- to the synthesis of vitamin A in the human body;
- cell growth stimulation;
- transporting amino acids along with blood to various organs and systems( in particular, the liver, thyroid, kidneys);
- normal body thermoregulation;
- lipid breakdown;
- removal of excess cholesterol from the blood;
- full brain activity;
- normal functioning of the cardiovascular system;
- transportation of oxygen to internal organs;
- maintaining mental alertness.
If we talk about what the hormone T3 is responsible for in young children, then their mental development depends on its level in the blood. With an insufficient amount of this substance, negative changes occur in the work of the thyroid gland, which, in turn, causes the development of various diseases and the overall development of the organism.
Note. Thyroid hormone triiodothyronine, or T3 is determined by conducting a clinical blood test. In case of any deviations from the norm, instrumental diagnostic procedures are mandatory by the endocrinologist. Comprehensive examination helps to make an accurate diagnosis and prescribe an effective treatment.to contents ↑
Norm triiodothyronine in the blood test for T3
Thyroid hormones T3 can be free and common, and since there is a significant difference between them, there are differences in their normal indicators. Also, differences exist between their units. Total T3 is measured in nanomoles( nmol / l), and free - in picomoles( pmol / l).
The t3 hormone levels depend on several factors:
- patient's age;
- season( an increased concentration of the hormone is observed in winter);
- physical exertion;
- sex( in women, the level of the hormone ft3 is lower than that of men, by 5-10%).
Norm T3 free during pregnancy directly depends on its duration. Thus, in the first trimester, the level of this substance may be significantly increased, but as the fetus grows, it will decrease. In the end, at the last term, the indicators will be the most minimal.
Reducing the level of T3 in expectant mothers is a normal phenomenon, since the development of a new life is a strong stress for the body. In addition, hormonal changes take place, which also affects the hormone-producing function of the thyroid gland.
The rate of free T3 in adults can vary from 3.54 to 10.2 pmol / l of blood. However, sometimes too high or, conversely, a low concentration of this substance may not be related to any diseases. In addition, in different laboratories the analysis on T3 may give different results. This is due to the equipment used for the test.
Note. The level of the hormone triiodothyronine in several tests, performed one after the other, may be the same, but this is not always the norm. The organism of each person is individual, therefore, what is considered optimal for one will be a serious deviation for the other.
Norm T3 free in men and women is the same, in children it differs by sex. After they reach adolescence, these figures become identical to each other.to contents ↑
When an analysis is prescribed for triiodothyronine
What is this analysis for T3 free, what is it for and what does it indicate? The study of the blood sample is carried out strictly according to the indications, which include:
- increased excitability;
- unreasonable attacks of aggression;
- frequent emptying of the bladder;
- general weakness;
- causeless sweating;
- sharp deviations in body weight( one way or the other), etc.
If a patient has such complaints, the doctor prescribes a T3 hormone test, based on the results of which a preliminary diagnosis can be made. Often, the study shows deviations in the thyroid gland, but there may be other reasons for deviations from the normal indicators of this substance in the blood.to contents ↑
What analysis to take?
Often the question arises, which test for T3 is free or common? This substance is in 2 states: associated with protein compounds and free. However, a more significant role is given to the second, since free T3 is the substance that has high biological activity, while the common one is a specific reserve substance.
To date, doctors prefer to perform an analysis on T3 free, because it gives the most accurate results. In addition, various factors may influence the overall triiodothyronine levels.
T3 is a rather complex hormone, so before a clinical study of blood, the patient must carefully prepare for this process. If you do not follow the rules of preparation for the collection of biological material, then the reliability of the results obtained is out of the question.to contents ↑
Abnormalities of triiodothyronine
A blood test for T3 is not the only diagnostic procedure with which you can immediately make an accurate diagnosis and prescribe an adequate treatment. However, it is possible to point out certain health problems. In addition, this analysis can help determine the cause of the ailment in each case.to contents ↑
Increased T3 levelAnother reason is iodine deficiency goiter, which is an enlargement of one or both( bilateral) glands.
Often, triiodothyronine is oversupplied with hormonal drugs. In particular, in women it may be associated with excessive or prolonged use of hormonal contraceptives. However, a sharp jump in the level of T3 can occur with the abuse of other groups of medications( barbiturates, statins, etc.).to contents ↑
Drop in T3 level
Development of T3 deficiency can occur in the background:
- thyroiditis Hashimoto( a disease in which immunity begins to destroy thyroid cells);
- hormone-producing thyroid function disorders( in particular, insufficient hormone production);
- undergone surgery to remove the thyroid gland( full or partial);
- of the course or current course of therapy using radioactive iodine;
- receiving iodine-containing drugs.
Need to know that the concentration of hormones never decreases in a chaotic manner. First, the fall of T4 occurs, and only then does the deficiency of triiodothyronine develop. At the same time, the body tries to replenish the reserves of this substance as much as possible by increasing the intensity of the thyroid gland.
Anyway, such a deviation cannot be allowed to take its course, for violations of the thyroid gland can be a trigger for more serious and dangerous health problems.