Norm basophils in the blood. Reasons for the decline

Basophils are called white cells in the blood that occur in the granulocyte process in the bone marrow, then a small amount of them travels into the bloodstream, as well as into tissues and organs. Basophils consist of large kernels, granules and lobules, which include the active components necessary for the control and destruction of foreign components in the body. Basophils, as well as eosinophils and neutrophils, belong to the subgroup of leukocytes, and are usually activated in the presence of an inflammatory process or reaction in the body.

Table of Contents:
  • What are blood basophils?
  • Norm in adults and children
  • Exceeding the rate of basophils in the blood
  • Basophils lowered

When taking blood, in laboratory conditions all elements in the leukocyte formula are counted, because each subgroup has its own role in the human body and using the detected result can be detected in timeor suspect a particular abnormality or pathology. In order to be able to independently understand the results of their analyzes, you need to have an idea what cells are responsible for what and what their rate should be. Today we will talk about what basophils are in blood analysis, what is their role, and what may be indicated by their deviation from the standard values.

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What are blood basophils?

Sometimes basophils are called blood scouts. Due to the fact that a single cell contains a lot of highly active substances serotonin, prostagladins, histamine and leukotrienes, the basophils immediately release all their contents at the first contact with a foreign particle or allergen, thereby blocking the "enemy".Therefore, it is not by chance that the basophils jokingly called scouts; their main task is to first find the enemy, tie him up and call other forces for help that will cope with him and carry out a sweep.

Apart from the fact that basophils together with other leukocyte structures take part in various inflammatory processes, their main function is considered to be participation in allergic effects on the body. Also, these white blood cells play a significant role in the process of blood clotting, ensuring blood flow in small vessels.

This is not the last thing that basophils in the blood are responsible for. There is another important role of these granular leukocytes, to remove various poisons from the body. Including, when the bites of poisonous insects or snakes, basophils can slow down the action of toxic substances, or completely eliminate them.

According to the content of basophils in one or another quantity, it is possible to draw some conclusions about the state of health or to identify any malfunction, but first you need to know what the established norm of basophils is in the blood.

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Norm in adults and children

Since basophils are a component of the leukocyte formula, their number is measured as a percentage of the main number of white blood cells. For adults and children there are established limits at which the indicator is normal.

The content of basophils in the blood of an adult is considered normal if the index is in the range from 1 to 5%.If the parameter is considered in terms of the number of cells per liter of blood, then the absolute content of basophils normally should not exceed 0.05 * 109 / l.

For children, the indicator is normal, if it ranges from 0.4 to 1%.If the results are strongly overestimated, it is a signal that certain factors adversely affect the children's body, or inflammatory or allergic processes occur.

The rate of basophils in the blood of women may vary slightly due to some physiological and natural processes. For example, a slight increase in the indicator is observed during menstruation, or when ovulation occurs, because at this time the level of estrogen in the blood rises, which in turn affects the quantitative level of basophils. Also basophils, the norm in women changes when taking certain hormonal drugs, estrogen and corticosteroids.

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Excess of the basophil rate in the blood

If the index significantly deviates from the norm in a big way, then it is probably a disease like basophilia. The causes of this condition are very diverse, and may be physiological and pathological in nature.

The level may be overestimated if a person has a final recovery stage after an acute infection or inflammation. Also, the reasons for the increase in basophils in the blood may be associated with the presence of the patient's disease in a chronic form. Often, the increase in basophils affects the lack of iron in the body.

For more information on the reasons for raising a child or an adult, see http: //vseproanalizy.ru/. Analizyi-krovi / pochemu-povyishenyi-bazofilyi-v-krovi.html

In medical practice, basophilia is encountered rather rarely. However, an excessive increase in white granular cells may indicate the presence of certain pathological conditions and diseases, such as:

  • acute hepatitis;
  • lung or bronchus cancer;
  • thyroid malfunction;
  • diabetes;
  • spleen removal;
  • various types of intoxication;
  • acute gastrointestinal tract pathology: ulcer or ulcerative colitis, gastritis, and others;
  • blood disorders, for example.myeloid leukemia or acute leukemia;
  • chicken pox;
  • X-rays;
  • acute viral infections;
  • allergic manifestations.

Basophils are most often involved in allergic inflammation, i.e.in hypersensitivity reactions of the instant and delayed type.

If you detect an increased number of basophils in the blood, you should not postpone the visit to the doctor. The method of clinical and diagnostic studies, examination and additional tests, the doctor will determine the cause of basophilia and prescribe adequate treatment of the underlying disease.

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Basophils decreased

The absence of basophils in the blood or a significant decrease in their level is called basopenia. Such a condition can be diagnosed when the content of basophils in the peripheral blood is less than 0.01 * 109 / l. It is problematic even to specialists to make concrete conclusions immediately, however, it is often a question of depleting the leukocyte stock in the body. If basophils are reduced in an adult, the causes can be quite different, the most common ones are:

  • long-term acute infectious diseases;
  • depletion of the body;
  • stressful situations, prolonged nerve overload;
  • increased physical exertion;
  • hyperthyroidism - a significant increase and hyperactivity of thyroid hormones;
  • long-term use of prednisolone or other types of natural hormone hormones;
  • pneumonia in the acute stage;
  • Itsenko-Cushing's disease;

The level of basophils often decreases in the first trimester of pregnancy, due to the effect on the body of the hormone progesterone and the total volume of the liquid fraction of the blood is increased.

If you find in the blood test report that basophils are missing, what does this mean? You should not immediately sound the alarm and think up any diagnoses or even self-medicate yourself, you should consult a doctor for clarification, because not all situations leading to a decrease in the level of basophils require an immediate response. Often the indicator is normalized with time independently. If basophils are 0 in an adult, that is, they are not found at all in blood smears, this may be the limit of the norm. It is impossible to ignore any deviations from the norm, but you should not panic either.

A decrease in the absolute content of basophils in the blood, most often does not carry with it a special diagnostic value, due to the negligibly small concentration of basophils in the peripheral blood. For a more complete picture, this absolute figure is compared with relative.

How to normalize the level of certain cells in the blood, it is necessary to discuss with a specialist, sometimes you just need to stop taking certain medications or follow a special diet with the content of dairy products, vegetables and fruits

Stay healthy!