Proliferation of bacteria in the small intestine


10 signs of a syndrome of enhanced bacterial growth in the small intestine

Do you know the feelingabdominal distentiona few hours after eating? Sometimes, sometimes even have to unbuckle the belt or buttons on the trousers?

Today, this problem is familiar to many people not by hearsay. Many of us wake up in the morning with a flat and tight belly, and by the evening it is bloated and heavy.

Bloating, even a small one, can talk about the presence of an inflammatory process in the intestine.If bloating is accompanied by gas and unpleasant state of health, the reasons for this may be the intolerance of certain food or intestinal infection, known as the syndrome of enhanced bacterial growth in a thin intestines.

What is the syndrome of enhanced bacterial growth in the small intestine?

Syndrome of enhanced bacterial growth in the small intestine# 8212; An infection that develops as a result of a disturbance in the balance of reproduction of intestinal bacteria.

The number of bacteria that live in our intestines suddenly starts to grow. What provokes this growth?

The cause of this can be malnutrition: a large number of foods rich in carbohydrates, alcohol, semi-finished products, refined sugars and flour.

The fact is that these products create a breeding ground for the growth and reproduction of bacteria and have a negative effect on fatty acids of the short chain, as a result of which wewe suffer from gasesand bloating.

Some kinds of bacteria are able to decompose bile salts, because of what our body stops absorbing fats properly, as a result of which a person develops diarrhea.

Finally, some bacteria produce toxins that damage the mucosa of the small intestine.As a result, our intestines lose the ability to absorb the nutrients our body needs.

Syndrome of enhanced bacterial growth in the small intestine: symptoms

It is worth noting thatsyndrome of increased bacterial growth in the small intestinedoes not have typical symptoms that would be characteristic only for this disorder.Therefore, these symptoms may well be signs of other diseases and disorders.

If you are often concerned about several of the symptoms listed below, it is better to see a doctor for a correct diagnosis:

  • Gases.
  • Bloating.
  • Poor absorption of fats.
  • Intolerance to substances such as lactose, gluten, caffeine, fructose, etc.
  • Pain and colic in the abdomen.
  • Constipation.
  • Irritable bowel syndrome or inflammatory bowel disease.
  • If you suffer from chronic fatigue or diseases such as diabetes or fibromyalgia, autoimmune diseases, neuromuscular disorders, and the like.
  • Lack of vitamins and minerals, especially vitamin B12.
  • Diarrhea.

What causes the increased multiplication of bacteria?

Excessive growth in the number of bacteria occurs due to a violation of the natural process of digestion, during which the bacteria move along the intestine along with the digestible food.

Thus, damage to the nerve endings or musculature of the intestine can lead to the accumulation of bacterial remains in the small intestine, which, in turn, can cause an increase in the number of bacteria.

There are diseases, such as, for example,diabetes,which affect the state of the muscles of the intestine, which in the future provokes the multiplication of bacteria.

Among other causes of the syndrome of increased bacterial growth in the small intestine and atypical concentrations of bacteria, it can be noted that the surgical operations carried out onintestineor Crohn's disease.

Also, the infringement of the flora of the intestines can lead to the taking of certain medications (antibiotics, drugs blocking steroids and acids).

In addition, as we have already said, one of the main reasons for the increased multiplication of bacteria in the intestines is the wrong diet:excessive consumption of alcoholic beverages, as well as foods high in carbohydrates and sugars, flour products.

Analyzes for determining the presence of the syndrome of enhanced bacterial growth

There is an analysis that can be done at home. It consists in conducting a respiratory test. The sample is carried out on an empty stomach (before the analysis can not eat for 12 hours). It is necessary to exhale into a small ball, then take a certain amount of sugar and repeat the samples every 15 minutes for three hours.

This test is quite heavy due to the need to carry it on an empty stomach. But he is able to detect the presence of such diseases as the syndrome of increased bacterial growth in the small intestine, gluten enteropathy and insufficiencypancreas.

In the clinic or medical center, the presence of this disorder can be determined by the results of urine and feces analysis.Before conducting these tests, you should consult your doctor and tell him about all the symptoms of the ailment.


The main recommendation is to reduce the consumption of carbohydrates, refined flour and sugars. Alcohol should also be avoided.

If you are forced to take any medications, it will be better to consult a doctor. As a rule, in order to reduce the number of bacteria in the intestine, antibiotics are prescribed.It is very important not to engage in self-medication.

Syndrome of excessive bacterial growth # 8212; Diagnosis and treatment

Syndrome of excessive bacterial growth# 8212; this excessive reproduction in the small intestine of microorganisms, colonize mainly the large intestine, which leads to a violation of digestion and absorption, before fats and vitamin B12.Causes. mainly transferred gastroejunostomy and vagotomy, pyloroplasty and autonomic diabetic neuropathy; less often # 8212; diverticulum. "Blind loop intestinal stenosis, motor disorders (for example, with systemic scleroderma), immunodeficiencies, anacidnost gastric juice (for example, with prolonged treatment with proton inhibitors pumps). The consequences of excessive bacterial growth: deconjugation of bile salts, which leads to a deterioration in the digestion of fats → steatorrhea and impaired absorption of fat-soluble vitamins; exhaustion of vitamin B12 → megaloblastic anemia; damages of enterocytes of intestinal villi and digestion disorders of disaccharides; increased entry into the bloodstream of antigens bacteria.


Classic symptoms:chronic steatorrhea and megaloblastic anemia. Others: weight loss and hypotrophy, abdominal pain. flatulence, the formation of a large number of gases, swelling (syndrome of intestinal protein loss), symptoms of deficiency of vitamins A and D (osteomalacia and osteoporosis, tetany, trophic disorders of the epidermis, night blindness), symptoms of vitamin B12 deficiency (ataxia and peripheral neuropathy), nodal erythema, spotted-papular rash. Can be observed (especially in patients after the formation of a bypass anastomosis of jejunum with ileum): glomerulonephritis, hepatitis or steatosis of the liver, arthritis.


1. Laboratory tests: macrocytic anemia, hypoalbuminemia; other abnormalities, depending on the clinical picture and lesions.

2. GIT: may reveal passage disorders or anatomical deficiency (eg, diverticulum, doubling, "blind loop intestinal stenosis).

3. Fecal analysis for fat: microscopic evaluation of a fresh feces preparation, when staining with 1% Sudan III solution # 8212; increase in the number of droplets of fat in the feces.

4. Inoculation of intestinal contents: quantitative and qualitative bacteriological analysis of the contents (taken with the aid of a probe inserted through the nose or in endoscopy) from proximal segment of the small intestine and duodenum, which is recognized by some clinicians as the gold standard for the diagnosis of excess bacterial syndrome growth. Positive result # 8212; anaerobic bacteria or E. coli of 106 cfu / ml.

5. Hydrogen respiratory test with glucose # 8212; the diagnostic value is positive (specificity 83%).

A single diagnostic test allows you to unambiguously establish a diagnosis, no. Often, confirmation is a positive response to empirical antibacterial treatment.

Treatment of the syndrome of excessive bacterial growth

1. Treatment of underlying illness or elimination of factors contribute to excessive bacterial growth.

  • 1) preparations containing triglycerides with an average chain length of # 8212; with the aim of facilitating the absorption of fats;
  • 2) in case of intolerance of disaccharides → the lactose content should be limited in the diet;
  • 3) supplements with vitamins A, D, E and B12, in case of deficiency.

3. Antibacterial treatment: is of prime importance. Within 10 days, it is necessary to use drugs that are active against gram-negative aerobic and anaerobic bacteria. In case of relapse of symptoms, the second cycle of treatment # 8212; within 4-8 weeks. The drug of the first choice # 8212; Metronidazole p / o 250-500 mg 2-3 × per day. Alternative drugs (p / o): tetracycline 250 mg 4 × per day, amoxicillin with clavulanic acid 875 mg 2 × per day, cotrimoxazole 960 mg 2 × per day, ciprofloxacin 500 mg 2 × per day, norfloxacin 400 mg 2 × in day. Vancomycin 125 mg 4 × per day.

4. Auxiliary treatment: cholestyramine (PMS-cholestyramine REGULAR) # 8212; reduces the intensity of diarrhea; prokinetic drugs # 8212; ex. erythromycin.


Royal Canin Gastro Intestinal Low Fat with the minimum fat content for dogs with diarrhea and pancreatitis

Royal Canin Gastro Intestinal Low Fat- veterinary medical food for dogs with diarrhea and pancreatitis. Contains a limited amount of fat, which allows to reduce the level of triglycerides in the blood in just 8 weeks.

  • Acute and chronic diarrhea
  • Acute and chronic pancreatitis
  • Hyperlipidemia
  • Lymphangiectasia - exudative enteropathy
  • Proliferation of bacteria in the small intestine
  • Exocrine pancreatic insufficiency
  • Pregnancy and lactemia

Duration of the course of application:

Duration of the diet varies depending on the severity of the symptoms of digestive disorders.

For the optimal functioning of the digestive system, it is necessary to observe the daily ration and increase its multiplicity of feedings per day.

  • Safety of the digestive system: a combination of high-quality proteins with a high degree of digestibility (L.I.P. proteins), prebiotics (fructo-oligosaccharides and mannan oligosaccharides), beet pulp, rice and fish oil provides maximum safety digestion
  • Low concentration of fats in the diet improves digestive function in dogs suffering from hyperlipidemia or acute pancreatitis
  • Low content of soluble fiber reduces excessive fermentation in the thick intestine. The low content of insoluble fiber helps to avoid energy costs for its digestion, and also to minimize the loss of palatability of the diet
  • A complex of antioxidants of synergistic action reduces the level of oxidative stress and fights free radicals

Helpful information:
"Less is better!". This is how nutritionists assess the necessary level of fat in the diet for dogs suffering from digestive disorders, such as hyperlipidemia or lymphangiectasia.
Recent studies have shown that after using Gastro Intestinal Low Fat Canine for 8 weeks, 15 dwarf schnauzers, suffering from primary hyperlipidemia, the serum concentration of triglycerides (p 03) and cholesterol (p = 04).

Feed composition

Dry food:
Rice, dehydrated poultry meat, wheat, barley, animal protein hydrolyzate, beet pulp, animal fats, yeast, minerals, fructooligosaccharides (FOS), psyllium shell and seeds, fish oil, yeast hydrolyzate (source of mannan oligosaccharides), marigold extract of erect (source of lutein).

Additives (per kg):
Vitamin A: 11700 IU, Vitamin D3: 1000 IU, Iron: 43 mg, Iodine mg, Copper: 9 mg, Manganese: 57 mg, Zinc: 186 mg, Selenium 8 mg.

Wet food:
Pork liver, pork, corn, rice, minerals, vegetable fiber, beet pulp, taurine, extract yeast (source of mannan oligosaccharides), fish oil, extract of marigolds erect (source of lutein), microelements (incl. in chelate form), vitamins.

Additives (per kg):
Vitamin D3: 200 IU, Iron: 8 mg, Iodine 5 mg, Copper: 1 mg, Manganese mg, Zinc: 24 mg.

Nutrition recommendations

Recommended daily diet



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