Acute myeloblastic leukemia
Leukemia is a disease of the circulatory system, which is based on a violation of the structure of bone marrow cells. Acute myeloblastic leukemia is characterized by the active development of immature forms of blood molecules, which, after entering the blood, gradually replace erythrocytes, leukocytes and lymphocytes.
Among the main causes of this pathology, doctors distinguish between radiological exposure and contact with carcinogens.
The clinical picture of the disease is formed depending on the type of cells that have been subjected to oppression. So, for example, a decrease in the number of red blood cells is accompanied by anemia (pallor of the skin, general weakness, chronic fatigue and loss of efficiency). The lack of platelets is manifested by prolonged bleeding and arbitrary subcutaneous bruises. Deficiency of leukocytes causes frequent viral-bacterial diseases.
What to expect:
Relatively favorable result of therapy is observed with timely diagnosis. To date, with the help of chemotherapy, oncologists manage to achieve long-term remission or even complete recovery of such patients.
Acute myeloblastic leukemia - life prognosis:
A full and adequate treatment of cancer patients in 50% of clinical cases leads to healing. Terminal stages of blood oncology, as a rule, can not be cured, all medical activities are concentrated around palliative care.
Acute myeloblastic leukemia: modern treatment of patients
Oncological patients after confirmation of the diagnosis, as a rule, immediately undergo chemotherapy. The purpose of such treatment is to translate the disease into a stage of remission. Cytotoxic drugs, in most cases, are prescribed in combination with hormonal drugs. Intensive drug treatment depresses not only the synthesis of atypical cells, but also the formation of physiologically normal blood elements. In this regard, patients during therapy worsen the general condition, which manifests itself as general weakness, attacks of vomiting, spontaneous bleeding and malaise.
The positive result of chemotherapy, in general, comes in a few weeks. Many patients undergo restoration of the hematopoietic function. At the stage of clinical remission, oncologists are determined with further tactics of treatment. In oncological practice, patients with leukemia can undergo an operation on bone marrow transplantation or a series of chemotherapeutic procedures.
The main anticancer treatment, as a rule, is complemented by antiviral and detoxification therapy.
Acute myeloblastic leukemia mainly affects children aged 1-7 years. Mostly boys are ill. The prognosis of the disease is relatively favorable. According to statistics, a full recovery occurs in 65-85% of clinical cases, provided adequate and timely treatment. Survival rates increase after transplantation, which unfortunately has a number of contraindications.
These indicators are much worse in the detection of chronic leukemia, in which the average life expectancy is 5-7 years. Lethal outcomes are observed during blast crisis. Emergency therapeutic measures include the implementation of cytostatic therapy.
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How many live such patients?
A generally accepted medical opinion is that blast forms of leukemia without timely-initiated therapy in a short time cause death. Acute processes are much more manageable than chronic oncology.
So, for example, 95% of children in the early diagnosis of disease can achieve a stable remission. And now for the cancer patients with a chronic form, the forecast is unfavorable, which is caused by high mortality. The life expectancy of such patients is estimated in months and very rarely for years.
In oncological prognostication, great importance belongs to the age, stat and general health status of the cancer patient.
How much is left to live and what does it depend on?
Everyone knows that early diagnosis of cancer is a kind of guarantee for successful therapy. In this pathology there is one very insidious moment. In most people, the onset of primary symptoms occurs at the terminal stages of oncoforming. Thus, from the moment of detection of the first sign to the lethal outcome, it may take about three months.
According to statistics, the survival rate of children with this type of oncology is 10-20% higher than in the elderly. A great influence on the anti-cancer effect of therapy is provided by the patient's lifestyle and the general state of immune forces.
The greatest danger to the patient's life is the sudden aggravation of the oncological process or blast crisis. Such conditions often indicate ineffectiveness of treatment and the transfer of pathology to the terminal phase.
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How to prolong life?
To prolong the life of oncologists it is recommended to adhere to the following principles:
- Chemotherapy courses are conducted by several sequential procedures.
- Admission of anti-inflammatory drugs that block the side effects of cytotoxic drugs.
- Vitaminotherapy and immunomodulation. These measures are necessary to activate the defenses of the body.
- Conduction of bone marrow transplantation.Acute myeloblastic leukemia, who was treated with a surgical method, has the most favorable prognosis with a 90% survival rate of five years. The disadvantage of this technique is the cost and complexity of the surgical operation.