Does the ulcer go to cancer?


Ulcer and cancer are two interrelated concepts, since a ulcerative lesion of 2-15% has a tendency to malignant degeneration.

Symptoms and signs of a precancerous ulcer

Ulceris a limited defect in the mucous membrane of the gastrointestinal tract, which can also spread to the submucosa. In the emergence of peptic ulcer an essential role is played by a decrease in the protective properties of the organism and local damage to the integrity of the gastric wall.

The immune-inhibiting factors include:

  1. Nervous overstrain and frequent stress.
  2. Irrational and disproportionate nutrition.
  3. Tobacco smoking and abuse of strong alcoholic beverages.
  4. Frequent consumption of salty or peppery foods.
  5. Reception of antibiotics or non-steroidal anti-inflammatory drugs in tablet form.

Destructive factors include:

  1. Infection with Helikobakter Pilori.
  2. Excessive production of gastric juice, which includes hydrochloric acid and the enzyme - peptin.
  3. Chronic gastritis with high acidity.

The relatively high probability that

degeneration of the ulcer into canceroccurs against a background of chronic gastritis, necessitates differential diagnosis. Symptoms of peptic ulcer include:

  • Pain syndrome. The occurrence of pain immediately after eating is considered a key sign of a stomach ulcer. If the patient complains of the so-called "hungry pain then this indicates a peptic ulcer of the duodenum.
  • Frequent heartburn and belching.
  • Often after eating, patients experience nausea and vomiting.
  • Gradual decrease in body weight.

Whenthe ulcer becomes cancer, the above symptoms are aggravated and there are additional signs and manifestations of stomach cancer.

Can an ulcer go to cancer?

The fact of a malignant degeneration of a stomach ulcer is considered a reality. But the frequency of occurrence of such a phenomenon is still a contentious quantity. According to many experts, 2-14% of cancer patients before the formation of malignant neoplasms had a peptic ulcer.


The greatest amount of malignancy is observed with long-lasting non-healing ulcers, the size of which varies from 2 cm to, cm. In such cases, the x-ray doctor ascertains the infiltration compaction of the outer edge of the defect of the gastric mucosa. Further progression of ulcerative lesions in the form of an increase in the volume of the lesion focus and the formation of roller-shaped ulcer boundaries, causes oncological alertness and precancer. Patients in such cases should immediately undergo a comprehensive diagnosis of the state of the digestive system.

Symptoms and signs of the degeneration of ulcers in cancer

Signs of a malignant transformation of a stomach ulcer include two types of symptoms:

  1. General-economic violations:
  • Feeling of constant fatigue.
  • Sharp decrease in appetite and body weight.
  • Rapid fatigue and general malaise.
  1. Local Symptoms:
  • Bloating and a feeling of overcrowding in the stomach after taking even a small amount of food.
  • Increased attacks of nausea and vomiting.
  • Periodic aching pain in the upper third of the abdomen, which can intensify after eating.
  • Chronic heartburn and impaired swallowing function.
  • Signs of blood loss. Patients with cancer with malignant neoplasms of the stomach often note the blood contents in the vomit and a loose stool of dark color.

Differential diagnosis of ulcers and carcinomas of the stomach

To establish a definitive diagnosis, the oncologist, in addition to analyzing the subjective complaints of the patient, requires the following diagnostic procedures:

  • Endoscopy:

The technique allows you to visually inspect the internal surface of the stomach with an optical device. In the course of this study, the physician can, if necessary, remove the pathological tissue for laboratory analysis.

  • Radiography:

On the x-ray image of the organs of the gastrointestinal tract, the pathological focus and its size can be traced.

  • CT scan:

Determines the exact location and form of the malignant neoplasm.

  • Laparoscopic examination:

It is carried out to diagnose the spread of the tumor process in the abdominal cavity.

  • Biopsy:

This method provides a microscopic examination of a small area of ​​mutated tissue. Based on the histology and cytology of the biopsy specimen, the final oncological diagnosis is made.

It is important to know:Stomach cancer: symptoms and manifestation

Treatment if the ulcer becomes cancer

The methods of treatment of ulcerous and oncological lesions of the stomach differ significantly:

For the therapy of ulcers of the gastrointestinal tract, a conservative method is used, which includes the administration of the following drugs:

  1. Antimicrobial agents aimed at the destruction of Helicobakter pylori.
  2. Antacids.
  3. Enveloping drugs that protect the gastric wall from the effects of physical and chemical irritants.
  4. The drugs that suppress the secretory function of the stomach. This ensures a decrease in the acidity of gastric juice.

A key method of therapy for a malignant neoplasm of the stomach is a surgical operation. Radical intervention is shown in the early stages of the disease in the absence of secondary oncological foci. Surgery in this case includes complete or partial excision of the organ.

Additional anticancer techniques include chemotherapy and ionizing radiation. In the later stages of cancerous growth, palliative therapy is indicated for oncological patients (relief of individual symptoms of the tumor).

It is important to know:Stomach cancer: symptoms, how many live?

Prognosis for ulcers and stomach cancer

Ulcer, cancer are diseases that have a completely opposite prognosis. So, ulcerative lesion with observance of all the doctor's recommendations has a favorable outcome. The mucosal defect is ultimately replaced by a scar.Rebirth of an ulcer in cancercarries a danger to the life of the patient. The index of five-year survival of cancer patients in the early stages of gastric cancer does not exceed 50%.


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