Chemotherapy for gastric cancer
Treatment of stomach cancer in the first 2 stages involves surgery, after which additional procedures are prescribed. Chemotherapy for gastric cancer is an obligatory measure for successful treatment. It means taking medications intravenously or in the form of tablets. Sometimes one medicine is used, and sometimes - their combination. As a rule, radiotherapy is also prescribed.
Feasibility of the course
The course of chemotherapy should pass any patient who plans to overcome stomach cancer. Therefore, treatment is advisable, because:
- Medicines are capable of destroying cells that are prone to tumors.
- The possibility of metastasis is significantly reduced.
- The risk of relapse significantly decreases.
- The patient's life is prolonged for an indefinite period.
In rare cases, chemotherapy is advisable before surgery, but it can only be prescribed by a doctor after appropriate studies, procedures and conclusions.
Indications for conduction
Chemotherapy is not prescribed for all patients with stomach cancer.
Indications for its conduct are as follows:
- The need for preparation for surgery.
- The spread of damaged cells to the inner surface of the peritoneum.
- Sudden detection of metastases in the liver.
- The need to reduce the size of an inoperable tumor.
- Symptomatics is too strongly pronounced and it is necessary to neutralize it to alleviate the patient's condition.
It is worth noting that the indications for the course of chemotherapy depend on the nature and type of tumor. In connection with this, this treatment is divided into categories:
It is prescribed for patients who can not or can not promptly remove a neoplasm if metastases are present or the patient refuses surgical intervention. In this case, the treatment is aimed at the fact that drugs prolong the life of the patient, improve its quality, relieve pain, stop the growth and development of malignant cells.
Therapy reduces the area of spread of the focus of the disease and greatly facilitates the process of surgery for the surgeon.
Treatment eliminates metastases in order to prevent relapse.
It is carried out only intravenously or with the help infuzomata. Doctors advise it with a common stomach cancer.
It is conducted comparatively rarely. It is prescribed only in one case, if the cancer cells are on the inside of the abdominal cavity and supplemented with ascites - this is the accumulation of excess fluid. In this case, the liquid is first pumped out, after which the drugs are delivered by the catheter immediately to the damaged site, and in addition the person uses substances that inhibit the emetic reflexes.
Pharmacological infusions in the hepatic artery
Appointed only when a metastasis is found in the liver. This is currently considered an experimental treatment and it is conducted under general anesthesia. The surgeon makes an incision in the abdominal cavity through which the necessary drugs are delivered to the liver.
The course of the disease and the course of treatment are followed by specialists - a gastroenterologist and an oncologist.
Contraindications to the course
There are certain contraindications to the course of treatment. They are divided into absolute, which relate to all, and relative, which can be neglected, if the doctor agrees.
Absolute contraindications include:
- Chronic kidney and liver pathologies;
- Infectious pathologies in severe form;
- Diseases of the human psyche;
- The obstructed bile ducts;
- Gradual deterioration of health and general health of the patient;
- Non-invasive oncological disease;
- The availability of certificates from several doctors that in this case, chemotherapy is inappropriate, ineffective and will not bring positive results.
Relative contraindications are as follows:
- The presence of the human immunodeficiency virus;
- Rheumatoid arthritis in the patient;
- Elderly or too young age of the patient;
- Recent therapy with the use of antibiotics and antiepileptic drugs.
Chemotherapy is a step that entails many consequences and can lead to a worsening of the patient's condition. Therefore, the attending physician should carefully weigh all the factors before prescribing such treatment to the patient. As you progress through the course, you need to constantly monitor and monitor the progress of treatment. The physician should have a complete understanding of how chemotherapy will affect the body of a particular patient.
A positive medical decision about the need for a course is influenced by such factors:
- References on the results of laboratory studies.
- Assessment of the general condition of the patient.
- Presence of pregnancy.
Even with the right approach to treatment, side effects can not be ruled out.
Advantages and on what depends efficiency?
Chemotherapy has obvious advantages. It can be a supplement to a surgical intervention or be an independent method of treatment. It significantly prolongs the life of the patient and increases the chances of a successful recovery.
There are factors on which the effectiveness of the course of chemotherapy depends:
- the stage at which cancer was detected;
- experience of the past similar treatment;
- various medical disorders;
- presence of chronic pathologies;
- age of the patient;
- tumor localization;
- individual features of the body.
In general, doctors emphasize the positive effect of the course of chemotherapy.
How to prepare for the event?
It is necessary to comply with all the recommendations that the doctor speaks about. Usually they are reduced to activities:
- Reception of infusion solutions.
- Application of hepatoprotectors.
- The use of agents that increase the metabolic activity of hepatocytes.
- Taking medications that reduce nausea.
Also, a doctor can prescribe a balanced diet for stomach cancer. This is due to the fact that drugs can aggressively affect the stomach environment. Therefore, the rules of nutrition, which the doctor says, are mandatory for each patient.
Usually nutrition is reduced to the fact that the food should be not heavy for the stomach, but to saturate the person with the necessary amount of energy.
What drugs are used?
The main drugs that are prescribed for the course of chemotherapy are:
- "5-Fluorouracil". It is usually administered intravenously and changes the structure of RNA, which destroys cancer cells;
- "Ftorafur". After intake, a substance is released in the body that fights against cancer cells;
- "Xeloda." The main substance affects only the affected tissue, it does not affect the healthy ones;
- "Gemcitabine." Interferes with the structure of DNA and RNA of damaged cells;
- "UFT". Getting into the body, it is transformed into an active substance with a pronounced antitumor effect.
Drugs can be administered individually or as a whole. The final decision on combining drugs is taken by the attending physician.
Possible side effects and how to avoid them?
Side effects often occur after a course of chemotherapy. It is impossible to avoid them, it is possible to eliminate only with the help of a correct way of life and appointments of the doctor, who should select methods of rehabilitation for each patient individually. Side effects include:
- nausea and vomiting;
- a sharp drop in immunity;
- internal bleeding;
- complete lack of appetite;
- excessive hair loss.
After the course, be sure to eat properly and take drugs that stimulate the immune system.
The cost of chemotherapy for gastric cancer is usually not very high. The initial consultation is about 6000 rubles, the course itself, depending on the type and complexity, from 5000 to 6000 rubles for session, and the cost of using diagnostic devices and constant monitoring of the doctor for the course of treatment is approximately 3000-4000 rubles.
Of course, the price is indicated conditionally. The total cost will depend on many factors and the complexity of treatment.
Thus, chemotherapy for gastric cancer is a highly desirable procedure that has a number of undeniable advantages. Under the guidance of an oncologist, a course can help overcome the disease and improve the quality of life..