What is dangerous malignant schwannoma?
Oncological lesion of the nervous tissue, which is formed from the Schwannian membrane, is predominantly benign in nature. Only 7% of such cases are formedmalignant schwannoma. Statistics say that the disease is most often diagnosed in middle-aged men.
What is the danger?
Schwannoma cancer character, as a rule, is localized in the area of the lower extremities. The main danger of the tumor is a rapid and aggressive growth, which can be accompanied by the formation of metastases. Secondary foci are formed in nearby bone tissues.
Malignant schwannoma is manifested by the following symptoms:
- Limited edema of soft tissues. In some cases, the disease can occur as a multiple knotty lesion of the lower extremities.
- Ulceration of the skin over the area of atypical growth.
- Periodic bouts of pain. This symptom is observed in 50% of cancer patients.
- Pathological fracture in the area of cancer cells spread to bone tissue.
Signs of malignant schwannoma
During palpation, the malignant focus is a limited tuberosity or a single knot. The development of cancer is largely determined by the microscopic structure of the tumor. For example, for a highly differentiated mutation, a slow increase in volume is characteristic, and for a low-grade oncology fast and aggressive growth is typical.
The consistency of the neoplasm is quite dense, which is explained by the high content of fibrous tissue in it. It should be noted that, as a rule, there are no signs of damage to nerve tissues.
What is included in the diagnosis?
In the diagnostic process, oncologist doctors introduce the following methods:
- Ultrasound examination, which provides comprehensive information about the location, size, form of the malignant focus.
- Radiography. Traditional X-ray examination reveals only changes in bone tissues, which is important in terms of diagnosing metastases.
- CT scan. Layer-by-layer scanning of the human body is considered an indispensable way of detecting a mutation.
- Biopsy. The surgeon uses a forceps or a syringe to collect biological material, which is then sent to a histological laboratory.
- Histological analysis. Microscopic examination of sections of pathological tissue is aimed at establishing a definitive diagnosis and ascertaining the extent of the spread of cancer.
Treatment of malignant schwannoma
Therapy of such a pathology is exclusively surgical. This malignant neoplasm, as a rule, does not respond to tonic radiation and cancer drugs. In this regard, in all clinical cases the tumor undergoes radical excision.
During the operation, the oncologist surgeon removes the modified tissues and a small part of the nearby healthy structures. This is necessary to ensure the prevention of recurrence, because in neighboring organs can be located tumor cells.
The scope of surgical intervention is determined individually. Often, specialists resort to radical resection of the lower limb with the removal of regional lymph nodes.
Prognosis of the disease
The ailment has a relatively favorable course. The five-year survival rate reaches 80%, and 60% of patients manage to survive 10 years after surgery.
Unfortunately,malignant schwannomavery often forms a re-tumor after treatment. The only way to achieve a positive prediction is timely diagnosis and adequate therapeutic tactics..