Because of what factors can a decrease in the monocyte count in the blood?
The qualitative composition of blood plays an important role in human life. When her formula is normal, a person feels well. What is the role of monocytes in the blood? How many of these blood components are normally contained, and are there any differences in normal age rates? Does the norm depend on how old the person is?
- General information about cells
- The purpose of monocytes
- Normal performance
- Deviations from the norm
- Level up
- Reduction of the quantitative indicator
General information about cells
Monocytes are one of the largest elements of blood. They belong to the leukocyte group. Since there are no granules in their cytoplasm, they are called agranulocytes.
The formation of these cells takes place inside the bone marrow. A full development passes and terminates in the bloodstream and lymph nodes. Movement is slow, because cells are large. As these cells mature, these leukocyte formations become macrophages or histiocytes.
The way they protect the human body is schematically shown in the video:
The purpose of monocytes
The functions of monocytes, like other leukocyte cells, are to protect the body from pathogenic microorganisms. The absolute content of these particles should always be normal. Although the quality of the immune system depends on how fully these cells perform their functions, their excess negatively affects the body.
In the blood, monocytes act as a kind of purifier. They are able to completely absorb even large particles, neutralizing them. In addition, the functions of monocytic cells are as follows:
- liberation of blood from clots, which prevents the formation of blood clots;
- neutralization of viruses and bacteria that enter the bloodstream;
- maintenance of normal functioning of the immune system;
- assistance in tissue repair after tumor disintegration;
- tissue regeneration after inflammatory processes.
It is noteworthy that although the main functions of these particles are the destruction of bacterial microparticles, they are not immediately sent to the focus of infection. The monocyte element is able to absorb and neutralize a particle of equal size. Therefore, most often the cell arrives "to the scene" a little later, removing dead leukocyte cells, microbes and other fragments.
Knowing what monocytes are, it becomes clear how much these blood components are important for a person's normal life. Without these compounds, the body would be very vulnerable. It is important to understand what is the norm of monocytes in the blood of women and men.
Monocytes in the blood test should be within normal limits. Although these components are extremely necessary, this does not mean that the more of them, the better. Deviations from the indicators indicate pathological processes.
The norm in the blood of men and women is this:
- monocytes Abs, 8 * 109 / l;
- in a percentage ratio of 2-9%.
The figures, which are indicated in percentage, indicate the number of monocytes in the blood from the total mass of leukocytes. The absolute value indicates the number of these cells in a liter of blood. Normally, for women and men, the figure is almost the same. Slightly affects him and the age of a person.
The index from 2-12% is normal for children under the age of 12 years. 3-11% - normal data for people over 12 years old.
It is noteworthy that a general blood test does not give a complete idea of how much monocytes are in the blood. It determines only the number of unripe cells at the time of laboratory testing. Some cells of this group are already in tissues and organs, and this does not show the results of the analyzes..
Attention! Because of the peculiarities of the female constitution, the number of monocytic cells in the blood varies depending on the day of the cycle, during menstruation, and also depends on the diet and the next meal..
In the analysis of blood, the level of monocytes in an adult does not practically differ from that of even a one-year-old child. Regardless of how old the kid is, the norm ranges from 2-12%.
Deviations from the norm
After receiving the results of laboratory blood tests, the decoding is performed by the attending physician. He has the necessary table and the knowledge, helping to put the correct diagnosis and to choose competent treatment.
When too high values of monocytic cells appear in the leukocyte formula, they speak of monocytosis. When the monocyte level is lowered, monocytopenia is diagnosed.
If the result of laboratory research has shown that the indicator is elevated, it can testify to the course of the inflammatory process, which is currently in the most active stage. The indicator rises in bacterial and viral infections, such as influenza and tuberculosis. The cause may be syphilis, the Epstein-Barr virus, brucellosis, rickettsiosis and parotitis.
Only a doctor can fully respond to all the patient's questions regarding his health, and then after the survey.
An increase in the level of monocytic cells occurs when the body is infected with various fungal infections. With infectious infection of the endocardium and inflammatory processes in the intestine, the same changes occur in the picture of the analyzes.
Some surgical interventions can lead to an increase in the number of monocytic cells in the blood stream. Gynecological manipulations, removal of appendicitis and performing other operations in the pelvic area often cause monocytosis.
Monocytosis develops in autoimmune diseases:
- lupus erythematosus;
- rheumatoid arthritis.
Pathology is often found in patients suffering from the growth of an oncological tumor. Symptom is present in blood diseases, such as polycythemia, acute leukemia, chronic myelogenous leukemia..
Attention! A slight increase in monocyte cell counts is possible at the stage of recovery after measles, rubella and sore throat..
Reduction of the quantitative indicator
The level of mono can be reduced in such cases:
- with a decrease in immunity;
- with anemia;
- with a shortage of B vitamins;
- with anemia.
If the parameters of monocytic cells do not meet the norm, the problem may be related to their synthesis in the body. In this case, it is worth paying attention to whether there are severe pathologies, such as leukemia or sepsis..
If you carefully pay attention to all the changes in the blood picture, with the help of only one laboratory analysis you can get a lot of valuable information about the state of health... .