Preparation for the analysis of CK, evaluation of results, norms and deviations

Blood test

Among the numerous medical tests prescribed by doctors in the process of examination, in order to establish a correct diagnosis, there is a blood test for kfc. Asking about what is kfc, it is worthwhile to understand that biochemical analysis is a much broader concept than simply determining the activity of kratin phosphokinase and its level in the patient's blood.

One of the indicators for the examination of the cardiovascular system


  • What is KFK?
  • Determination of CK as a stage of biochemical blood test
  • Combinations of isoenzymes
  • Preparation for the analysis
  • Evaluation of biochemistry results
  • The norm of CK in the body of a healthy person

What is KFK?

Determination of the activity of creatine phosphokinase (creatine kinase) in blood serum is the main component of a general biochemical blood test. Serum kfc is indicative of the degree of damage to muscle cells, leading to a disruption biological processes in the human body and the development of heart diseases, skeletal muscles and thyroid glands.

In the presence of even the slightest pathological changes in the human body, the level of creatine phosphokinase increases. In the absence of any disease, creatine phosphokinase, together with ATP (adenosine triphosphate), is converted into Creatine phosphate (present in a small amount), successfully cleaved during physical activity.

When examining a patient, the doctor in charge must assign a biochemical blood test to the patient, where he pays special attention to assessing the level of kfc.

Determination of CK as a stage of biochemical blood test

The blood test for kfc is a morning fence of the patient's venous blood on an empty stomach to determine the level of a specific enzyme - creatine phosphokinase.

The analysis of the creatine kinase is assigned to the following group of patients:

  • complaining of pain in the chest area;
  • injured muscles of the skeleton;
  • having various inflammatory processes;
  • having atrophy and dystrophy of muscles;
  • undergoing treatment in the cardiology department;
  • who are at risk for diseases of the kidneys, heart, thyroid, brain.

In the biochemical analysis of blood, the attending physician looks primarily at the creatine phosphokinase, elevated or, conversely, a lower level of which indicates serious violations that require additional study and immediate treatment.

Combinations of isoenzymes

Depending on which system of organs is failing, the following combinations of isoenzymes are distinguished:

  • KFK-MB;
  • KFK-MM;
  • KFK-BB.

If the isoenzyme of the CF combination prevails in the blood, then one can speak of heart diseases, such as myocardial infarction.

BB- isoenzyme signals a violation of the brain.

KFK-MMIn the blood serum is predominant in injuries to the muscles of the skeleton and lung diseases.


Preparation for the analysis

To obtain an adequate result, general medical recommendations should be observed:

  1. Observe the daily routine and, if possible, do not overexert.
  2. On the eve of the analysis, sleep at least 8 hours.
  3. Do not drink alcohol.
  4. Carefully monitor the intake of medications and their dosage.
  5. Monitor your diet, if possible, eliminate fried and fatty foods, do not drink carbonated drinks.
  6. To hand over the biochemical analysis of blood only on an empty stomach.
The observance or non-observance of the rules determines the result

Evaluation of biochemistry results

The results are deciphered by the attending physician. It is noteworthy that the level of CFC in the analysis of blood depends on such criteria:

  • floor;
  • race;
  • age;
  • body type.

Reduced enzyme content can be an indication that the body is affected, in the first place, by the liver or joints.

In addition to pathological conditions, the following factors may be responsible for the lowering of CKF:

  • age atrophy of muscle mass (old age);
  • pregnancy;
  • hormonal failure (thyroid dysfunction);
  • malnutrition;
  • anorexia.

Increase in the enzyme in the serum indicates a deviation in the lungs, brain, heart muscle (myocardium) or skeleton.

A significant increase (5-10 times) of the enzyme may indicate:

  • malignant tumors;
  • the period of newborn;
  • admission to blood sampling of certain medications;
  • postoperative period;
  • stress and excessive physical exertion;
  • reception of protein-containing drugs;
  • acute infectious diseases (meningitis, encephalitis, tetanus and others);
  • inflammation and trauma to the muscles of the skeleton;
  • cardiac disorders (tachycardia, myocardial infarction of coronary heart disease);
  • serious neurological and mental disorders (epilepsy, schizophrenia).

Sometimes the results of biochemistry can be erroneous because of non-compliance with the doctor's recommendations: taking sleeping pills or alcohol, drugs that correct blood cholesterol levels (statins). At the same time, the patient does not complain about anything and feels well. In this case, the biochemistry is re-administered.

The norm of CK in the body of a healthy person

The unit of measurement of the indicator of creatine phosphokinase in serum is 1 unit per liter (ED / L). When assessing the result, it is necessary to take into account the individual parameters of the blood donating person: his age, sex, weight, muscle mass.

When evaluating the results, several parameters are taken into account

In childhood, the presence of an enzyme in the blood is usually much higher than in an adult and can vary (depending on the child's age) from 123 to 650 units / liter. Normal indicators in healthy women - from 24 to 170 units / l, for men - from 24 to 190 units / liter. Consequently, in women the activity of the described enzyme is somewhat lower than that of men.


Thus, the biochemical analysis of blood is one of the most frequently prescribed tests for examination among men and women of different age groups. The level of creatine phosphokinase is considered an important criterion in assessing the condition of the patient's body, identifying serious pathologies, such as inflammation or trauma of skeletal muscles, myocardial infarction, inflammation of the brain membranes, cancer tumors, thyroid dysfunction glands.


To obtain the correct result of the analysis, it is necessary to strictly follow the doctor's recommendations, observe the regime of the day, do not abuse harmful food, be careful in taking medications.

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