How to take Saitotec to interrupt pregnancy?

Saitotec is a steroidal antiprogestagenic agent based on the synthesized active ingredient misoprostol, involved in the regulation of blood pressure, contractions of smooth muscles lining the blood vessels of the neck and body the uterus. In medical practice, Saitotec is used to terminate pregnancy as an alternative to vacuum aspiration and surgical abortion.

Pharmacological properties


Cytotec (cytotec) refers to prostaglandins, which affect the contractile activity of smooth muscles, blood circulation, the production of mucous secretions. The pharmaceutical company that sells Saitotec did not initially register a patent for the use of the drug in gynecological practice. This drug is widely used in the treatment of the gastrointestinal tract in ulcerative erosive processes. Despite the exclusion of the drug Saitotec from the scheme of drug abortion in domestic medical institutions, the drug is still used in obstetrics and gynecology.

Unlike foreign countries, in Russia, the drug-induced abortion of pregnancy takes only 10% -15% of all reported cases. Negative attitude towards the medical board gynecologists explain the lack of 100% certainty that the fetal egg has left the uterine cavity. The effectiveness of Saitoteka varies between 80% -98%, taking into account the regimen of intake, dose, individual sensitivity of the organism and other factors. However, official medical statistics confirm the higher effect of Saitotek compared to its predecessors.

Conducted clinical trials indicate the high efficiency of Saitotec (Misoprostol) in combination with Mifepristone, which increases sensitivity and contractile activity myometrium. Mifepristone analogues can be used:

  • Pencrofton (Russia);
  • Mytholian (China);
  • RU-486 (Russia);
  • Mifygin (France);
  • Mirolut (Russia).

These drugs contain the same concentration of hormone-like substance (200 mg), but differ in price, promotional packaging, the presence of additional components. Similar properties of hormonal drugs are not a reason for self-selection of a specific drug. Only the attending physician should indicate how to take the medicine to terminate the pregnancy.


Determination of effective dose

Conducting medical abortion is possible only for up to 6 weeks (up to 42 days amenorrhea). To achieve maximum therapeutic effect, Saitotek tablets for abortion are taken in combination with anti-gestagenic agents (Mifegin, Mifepristone).

Saitotec - instructions for conducting a pharmacist:

Mifygin (Mifepristone) The gap between taking drugs Saitotec Reception Features
600 mg (3 tablets of 200 mg) at one time 36-48 hours 400 μg (2 tablets of 200 μg each) Strictly under the supervision of a doctor

The combination of drugs increases the tone of the uterus due to the reduction of smooth muscles of the myometrium. Under the influence of drugs, the cervix of the uterus opens, and the fetal egg leaves the cavity along with bloody clots.

Instruction for abortion indicates the need for an abortion procedure strictly under supervision qualified medical personnel within 2 hours to provide emergency complications:

  • vomiting;
  • dizziness;
  • pain syndrome;
  • bleeding;
  • hyperthermia;
  • falling blood pressure;
  • allergic reaction.

Before using the tablets, it is advisable to take the last meal in 1 or 1 hour.

Between the reception of an anti-gestagenic drug and prostaglandins, the doctor evaluates the patient's condition. After the application of the cytotec, it is necessary to pass an ultrasound examination of the uterus to make sure that the fetal egg has left its cavity. The presence of bloody discharge is not a 100% guarantee that the pharmabort was successful. After 7-14 days, the ultrasound is repeated.

You can make sure of interruption of pregnancy by examining the blood for beta-chorionic gonadotropin. After successful use of the site, its level is gradually reduced.

If the fetal egg does not leave the uterine cavity, the doctor prescribes abortion by vacuum aspiration. Within a few days after a vacuum abortion, the level of the chorionic gonadotropin will be increased in the woman's body. This is normal, which does not mean that the pregnancy was not interrupted. Within 1-2 weeks the hormone level should stabilize.

Contraindications for use

Whether it is possible to carry out the pharmaboth with the help of Saitoteka, the gynecologist decides by preliminary studying the patient's history. The main contraindications to drug-induced termination of pregnancy are attributed to Saitotec:

  • pregnancy for a period of 6 weeks;
  • acute inflammation in the pelvic organs;
  • anemia;
  • arterial hypertension;
  • suspicion of ectopic pregnancy;
  • signs of an organism intoxication;
  • the presence of adhesions in the reproductive organs;
  • blood diseases;
  • arrhythmia;
  • chronic renal or hepatic insufficiency;
  • myoma of the uterus;
  • uterine hemorrhage in the anamnesis;
  • long-term admission of hormone replacement therapy;
  • abnormalities in the development of reproductive organs;
  • mental illness;
  • psychoemotional instability;
  • use of intrauterine contraceptives;
  • age to 18 years;
  • the presence of endocrine diseases in an anamnesis limits the use of Saitotek.

Self-administration of prostaglandins is unacceptable. The development of an anaphylactic reaction threatens to be fatal if there is no qualified medical care.

Unsuccessful attempt of medabort requires abortion with the help of surgical intervention. Preserve pregnancy in this case is meaningless, since the risk of anomalies in fetal development in the embryo is too high.

Dangerous Symptoms

The therapeutic effect is usually observed within 6 hours after taking the first tablet. The appearance of bloody discharge and moderate pain is considered a variant of the norm. The cause for concern and prompt treatment for medical help are symptoms such as:

  • bleeding breakthrough;
  • a sharp deterioration in the general condition;
  • severe weakness and signs of intoxication;
  • severe pain in the lower abdomen;
  • panic attack;
  • severe allergic reaction in the form of rashes, dyspnea;
  • tremor of extremities.

If the pain is insignificant, you can take an anesthetic: Nurofen, Paracetamol, Pentalgin. After taking the Mifepristone tablet, a doctor can inject a No-shpa injection to soften the expected painful spasms. The choice of an anesthetic drug should be decided in advance.

Severe pain syndrome is an alarm signal that requires emergency measures.

Artificial termination of pregnancy with the help of synthetic hormones is always a risk of violation of the natural menstrual cycle, the process of ovulation. The unreasonable use of anti-gestagen and prostaglandins threatens the appearance of problems with conception in the future. Deciding on the pharma, the woman must weigh the pros and cons: for the restoration of the hormonal background and the body as a whole can take months and even years.