C function of the reactive protein in women, which is indicated by the deviations and methods of treatment

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2017.08.23
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Blood test

A biochemical blood test is one of the most valuable laboratory tests that allows doctors to diagnose diseases in the early stages. It includes a mass of items that characterize the functions of the body. This list includes the C-reactive protein. It is a marker of inflammation in the body.

CRP is a specific substance produced by the liver and circulating in the blood in small amounts. This is considered the norm. With an exacerbation of chronic diseases or in the presence of acute inflammation, the protein values ​​increase. Also, an analysis is used to monitor the treatment of medication or surgical. To do this, a series of studies are conducted in dynamics, because the life span of the protein is small, in the acute phase of diseases it decreases even more and it is possible to trace the changes in concentration, which confirms the stage of the disease and the intensity flow.

Content

  • Functions of C-reactive protein
  • Changes in the level of CRP in normal and pathological conditions in women
  • Indications for the purpose of the assay
  • Preparation for the analysis
  • Procedure for sampling analysis

Functions of C-reactive protein

When the phases of the inflammatory process are deployed, the C-reactive protein is elevated. This activates the immune system, leads the organism's adaptive systems into a state of high alertness.

Main functions of reactive protein

The active process of protein synthesis is regulated by a special group of proinflammatory substances - interleukins, tumor necrosis factors.

An increase in the concentration of C-reactive protein in the blood leads to activation of immune cells, mainly T-lymphocytes, macrophages, platelets. Stimulates their work process of phagocytosis and transmission of information about genetically alien material to memory cells. Because of the specific functions of the activated cells (T-lymphocytes), the build-up in the blood of CRP during inflammation of the bacterial nature is more intense than in viral infections.

In the recent past, doctors used the indicator for the diagnosis of acute inflammation, which is included in the clinical analysis of blood-the rate of erythrocyte sedimentation. At the moment, the development of medical science is not a specific marker, in contrast to the C-reactive protein, its level is slow grows and lasts longer at a high level, hence the belated formulation of the diagnosis, the irrational time of the onset and abolition of antibacterial therapy.

Changes in the level of CRP in normal and pathological conditions in women

During life, the norm of C-reactive protein in women in the blood in the usual state, as in all adults, is relatively stable and amounts to 9 mg / l. Anything higher than these figures makes us think about the onset of an acute septic process in the body.

An interesting proven fact is the beneficial effect of breastfeeding on the female body. In girls who received mother's milk in infancy, the level of CRP is normally much lower than that of those who were on artificial feeding. This is the prevention of increased blood cholesterol levels and vascular disease.

Based only on the analysis of the diagnosis can not be made, so doctors use physical, instrumental and other types of examination. This is important, since there are situations when the C-reactive protein increases in women during menopause, with increased physical exertion. Taking oral contraceptives, steroid anabolic drugs, smoking and overweight also leads to an increase in CRP.

Role of DRR

C-reactive protein also grows in pregnancy, because the process of reorganization of immune processes in the body takes place for the child to carry out.

List of pathological conditions leading to an increase in C-reactive protein is extensive:

  • Bacterial infections: peritonitis, meningitis, pneumonia, nephritis, myocarditis.
  • Parasitic diseases: helminthiases, echinococcosis, toxoplasmosis, miases.
  • Autoimmune diseases: lupus, rheumatoid arthritis, scleroderma, psoriasis, multiple sclerosis, thyroiditis.
  • Tumors, especially malignant nature: melanoma, sarcoma, teratoma, leukemia, glioma.
  • Extensive areas of necrosis: cerebral stroke, pancreatic necrosis, myocardial infarction, gangrene of the extremities, necrosis of the intestine, large area burns, trauma or extensive surgical interventions.
  • Transplantation of organs and tissues, which reflects the development of rejection reaction of the type "host versus graft."

Of particular importance in recent years has been the control of the level of C-reactive protein in people with chronic diseases of the cardiovascular system, which in women, in view of the special hormonal background, is relevant.

Use an ultrasensitive biochemical analysis, the dynamic indicators of which in time will indicate an increased risk of developing dangerous states: myocardial infarction, ischemic or hemorrhagic stroke of the brain, thromboembolism, exacerbation of the cardiac insufficiency.

Indications for the purpose of the assay

Based on the conditions that lead to a change in the indications of the C-reactive protein in the blood, the doctor will prescribe the examination:

  1. If there is a suspicion of an infectious process, for differential diagnosis with autoimmune diseases. In both cases, the C-reactive protein is elevated, but to varying degrees.
  2. For the control and correction of drug therapy with hormonal steroid preparations, antibiotics.
  3. In the postoperative period, especially after urgent extensive surgical interventions, to understand how effective it was, the degree of intensity of inflammation and reparative processes.
  4. The analysis for the level of CRP is indicated for patients with chronic heart diseases to prevent vascular accidents.
  5. If you suspect or clarify the diagnosis of cancer.
  6. When reaching 60 years or more, it is recommended to monitor C-reactive protein values ​​once a year.
Sensitive marker for inflammation and pathology

Preparation for the analysis

To obtain real indicators of C-reactive protein and to avoid incorrect and untimely diagnosis it is recommended to follow certain recommendations on the eve of donating blood for research:

  1. To exclude psychoemotional and heavy physical activities.
  2. It is strictly forbidden to drink alcohol and smoke at least three days before the analysis.
  3. Avoid sudden temperature changes. Do not overcool and do not overheat, so hiking in a sauna or a sauna is better to postpone.
  4. Ideally, do not eat at least 12 hours before the test.
If this is not possible, then limit the fatty, fried, salty foods, adhere to a few days of vegetable-milk diet.

Procedure for sampling analysis

Blood for examination is taken from the peripheral vein by puncture with a conventional needle connected to a special tube - a vacuum tube. This reduces the risk of foreign substances entering the sample and the likelihood of an unreliable result.

Blood sampling

The change in the level of C-reactive protein does not mean anything. Especially in the blood of women, because there are many conditions that affect its increase, even in the absence of diseases. A reliable definitive diagnosis can be made only by a physician, based on the clinical picture, the level of CRP and other methods of investigation. Do not ignore the body's alarming signals and seek help in time for a healthy and healthy life.

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