How correctly do TSH analysis to get an objective result?
The organism's homeostasis is a complex system of interaction of chemical substances, in which some substances stimulate the production of others. The center of development of regulatory factors is the pituitary gland. Among the many substances that are secreted by the gland, there is a thyroid-stimulating hormone. It affects the intensity of hormonal secretion of the thyroid and parathyroid glands. The study on thyroid-stimulating hormone allows you to determine the hormonal background and the cause of the violation of the secretory function of the thyroid gland.
- Factors that affect the level of TG
- Recommendations for preparing for the analysis
- Explanation of results
- Norm TTG
- Thyrotropin increased
- Thyrotropin lowered
- Thyrotropin in pregnant women
This hormone has several synonyms (thyrotropin, tirotropin) and is indicated by the abbreviation TTG or TG.
Thyrotropin is a glycoprotein, produced in the pituitary gland and acting on the development of the thyroid gland triiodothyronine and thyroxine. These growth hormones are denoted by the abbreviation TIII and TIV, respectively. They are important regulators of energy metabolism in the body, control the exchange of lipids and proteins.
Thyotropotropins TIII and TIV are closely interrelated, therefore, in the study of thyroid function prescribe an analysis of all hormones: a blood test for TSH, total and free (not bound by blood proteins) TIII, TIV. This complex of studies is the best for obtaining a complete picture of thyroid function.
The level of these hormones has an inversely proportional relationship: when the level of thyroid hormones increases, the level of TG decreases. When thyroid hormones decrease, TG increases, stimulating secretion.
Factors that affect the level of TG
Normally, TG fluctuates during a day (high levels of tyrotropin level at night and decrease by evening).
The physiological fluctuations of thyrotropin include a decrease in pregnancy. During this period, from the women who are preparing to become a mother, regular testing of the hormone TSH is required.
The level of the hormone finely reacts to taking medications, to the condition of the organs. Thyrotropin can cause changes in their work. Symptoms, in which there are reasons to suspect a violation of thyrotropin secretion, and there is a need to take the test for TTG, are diverse. Therefore, any doctor can prescribe a referral to a laboratory TSH analysis: an endocrinologist, a gastroenterologist, a therapist.
- Signs of hypothyroidism (oppression of the thyroid gland), toxic goiter.
- With persistent infertility, impotence.
- Diseases of the cardiovascular system.
- Myopathy (dystrophic muscle damage).
- Amenorrhea (delay or absence of menstruation).
- Hypothermia (low body temperature, limbs).
- Alopecia (diffuse hair loss).
- Prolonged depression.
- Monitoring hormonal background during hormone replacement therapy.
- Delayed sexual, mental development of children.
Measured TTG in international units per liter (mU / l). For people who have problems with the thyroid, it is better to do an analysis of tirotropine twice a year. The doctor always advises the patient how to properly donate blood to a TSH.
Recommendations for preparing for the analysis
To obtain objective results, it is necessary to pass the analysis correctly. When preparing for delivery of blood, exclude the influence of exogenous factors, to which thyrotropin is sensitive. Preparation for analysis on tirotropin includes standard rules.
Recommendations how to prepare for delivery, whether it is possible to smoke and eat before the procedure:
- Blood to pass on an empty stomach. 8-10 hours before taking the test, you can not eat.
- Before the analysis of TTG, smoking, alcohol, hypothermia and overheating of the organism (staying on the beach, bath) are not allowed for 3 days.
- Limit physical activity, protect yourself from emotional overexcitation.
- After consultation with the doctor, the question of the temporary cancellation of hormonal preparations, complex vitamins with iodine content is considered.
- It matters when I take the test. The optimal time for the analysis is the morning hours from 9 to 11.
Explanation of results
According to the results of the analysis, the doctor makes a conclusion. The patient can not independently diagnose and decide whether he is healthy or not.
In the forms of the results of the analyzes, normal reference values are written for comparison. If a person is healthy and has met all the requirements for delivery in the laboratory TTG, then the results will be within the specified standard. The norm depends on how old the patient is:
- For newborns, the norm is in the range, -1,.
- For babies up to, months - from, to 1,.
- For children from, to 15 months - from, to,.
- For children from 15 months to 5 years - from, to,.
- In children from 5 to 15 years, the norm is, .
- In adults, from, to,.
The normal level of TG gradually decreases with age.
An increase in the level of thyrotropin can explain the cause of some diseases or be their consequence. To hand over the analysis of a blood is obligatory in such cases:
- Mental disorders, developmental lag, somatic disorders.
- Neoplasms, pituitary adenoma.
- Oppression of thyroid function, insufficient secretion of hormones (hypothyroidism).
- Syndrome associated with unregulated thyrotropin secretion.
- Complex of symptoms of immunity to thyroid hormones of the thyroid gland.
- Insufficient functioning of the adrenal glands.
- Defeat of thyroid gland inflammatory character (thyroiditis).
- Tumors in the mammary gland, lungs. These tumors can begin to secrete thyrotropin. This condition is called ectopic secretion.
- Preeclampsia (severe gestosis) in pregnant women.
Thyrotropin increases after cholecystectomy (a resection of the gallbladder), other operations, with hemodialysis, against the background of taking medications (β-blockers, neuroleptics, iodine preparations, prednisolone, etc.).
Reduction of thyrotropin indicates such problems;
- Chronic stress, emotional-mental deviation.
- Thyrotoxicosis (a poisoning of an organism by hormones of a thyroid gland) which has a different etiology (a toxic struma, long-term use of corticosteroids, thyroiditis of autoimmune origin, illiterate hormone replacement therapy).
- Pituitary trauma, death (necrosis) of pituitary cells.
Reduction of thyrotropin is observed during fasting. In athletes often increases TSH as a reaction to the uncontrolled intake of anabolics. Testosterone stimulates the secretion of the thyroid gland, and tirotropin decreases. In the treatment of tumors with cytostatics, the level of thyrotropin also decreases.
Thyrotropin in pregnant women
During pregnancy, the level of TG in the female body is reduced. In its normal course, the reduction of thyrotropin is associated with the production of chorionic gonadotropin. It is called the hormone of pregnant women. This hormone takes on the function of stimulating the thyroid gland to produce hormones.
If the level of thyrotropin remains high, then the life of the fetus is in danger. Therefore, every woman must necessarily pass an analysis on TTG when registering. Given the importance of analysis, the expectant mother should take the TSH analysis correctly, in accordance with all recommendations.
After an unsatisfactory blood test to lower the level of thyrotropin, pregnant women are prescribed levothyroxine sodium.
The level of thyrotropin during pregnancy varies. The lowest rate is observed at the beginning of the child's bearing. In those mothers who carry twins, triplets, the level of thyrotropin can be zero.
Video: TTG during pregnancy:
Everyone needs to know that abnormalities in TSH and TIII, TIV values do not necessarily indicate abnormalities in the thyroid gland... .